The role of ITAM- and ITIM-coupled receptors in platelet activation by collagen

Research output: Contribution to journalReview article

Standard

The role of ITAM- and ITIM-coupled receptors in platelet activation by collagen. / Watson, Steve; Asazuma, N; Atkinson, Ben; Berlanga, Oscar; Best, D; Bobe, R; Jarvis, G; Marshall, S; Snell, D; Stafford, M; Tulasne, D; Wilde, Johnathan; Wonerow, P; Frampton, Jonathan.

In: Journal of Thrombosis and Haemostasis, Vol. 86, No. 1, 01.07.2001, p. 276-88.

Research output: Contribution to journalReview article

Harvard

Watson, S, Asazuma, N, Atkinson, B, Berlanga, O, Best, D, Bobe, R, Jarvis, G, Marshall, S, Snell, D, Stafford, M, Tulasne, D, Wilde, J, Wonerow, P & Frampton, J 2001, 'The role of ITAM- and ITIM-coupled receptors in platelet activation by collagen', Journal of Thrombosis and Haemostasis, vol. 86, no. 1, pp. 276-88.

APA

Watson, S., Asazuma, N., Atkinson, B., Berlanga, O., Best, D., Bobe, R., Jarvis, G., Marshall, S., Snell, D., Stafford, M., Tulasne, D., Wilde, J., Wonerow, P., & Frampton, J. (2001). The role of ITAM- and ITIM-coupled receptors in platelet activation by collagen. Journal of Thrombosis and Haemostasis, 86(1), 276-88.

Vancouver

Author

Watson, Steve ; Asazuma, N ; Atkinson, Ben ; Berlanga, Oscar ; Best, D ; Bobe, R ; Jarvis, G ; Marshall, S ; Snell, D ; Stafford, M ; Tulasne, D ; Wilde, Johnathan ; Wonerow, P ; Frampton, Jonathan. / The role of ITAM- and ITIM-coupled receptors in platelet activation by collagen. In: Journal of Thrombosis and Haemostasis. 2001 ; Vol. 86, No. 1. pp. 276-88.

Bibtex

@article{ec5db8e0e5b34373adb986d1755f966f,
title = "The role of ITAM- and ITIM-coupled receptors in platelet activation by collagen",
abstract = "The major activation-inducing collagen receptor glycoprotein VI (GPVI) has been cloned within the last two years. It is a member of the Ig superfamily of proteins and is constitutively associated with the ITAM-bearing Fc receptor gamma-chain (FcR gamma-chain). GPVI signals through a pathway that involves several of the proteins used by Fc, B- and T-lymphocyte receptors and which takes place in glycolipid-enriched membrane domains in the plasma membrane known as GEMs. Responses to GPVI are regulated by PECAM-1 (CD31) and possibly other ITIM-bearing receptors. Despite a pivotal role for GPVI, there are important differences between signalling events to collagen and GPVI-specific ligands. This may reflect a role for co-receptors in the response to collagen.",
author = "Steve Watson and N Asazuma and Ben Atkinson and Oscar Berlanga and D Best and R Bobe and G Jarvis and S Marshall and D Snell and M Stafford and D Tulasne and Johnathan Wilde and P Wonerow and Jonathan Frampton",
year = "2001",
month = jul,
day = "1",
language = "English",
volume = "86",
pages = "276--88",
journal = "Journal of Thrombosis and Haemostasis",
issn = "1538-7933",
publisher = "Wiley",
number = "1",

}

RIS

TY - JOUR

T1 - The role of ITAM- and ITIM-coupled receptors in platelet activation by collagen

AU - Watson, Steve

AU - Asazuma, N

AU - Atkinson, Ben

AU - Berlanga, Oscar

AU - Best, D

AU - Bobe, R

AU - Jarvis, G

AU - Marshall, S

AU - Snell, D

AU - Stafford, M

AU - Tulasne, D

AU - Wilde, Johnathan

AU - Wonerow, P

AU - Frampton, Jonathan

PY - 2001/7/1

Y1 - 2001/7/1

N2 - The major activation-inducing collagen receptor glycoprotein VI (GPVI) has been cloned within the last two years. It is a member of the Ig superfamily of proteins and is constitutively associated with the ITAM-bearing Fc receptor gamma-chain (FcR gamma-chain). GPVI signals through a pathway that involves several of the proteins used by Fc, B- and T-lymphocyte receptors and which takes place in glycolipid-enriched membrane domains in the plasma membrane known as GEMs. Responses to GPVI are regulated by PECAM-1 (CD31) and possibly other ITIM-bearing receptors. Despite a pivotal role for GPVI, there are important differences between signalling events to collagen and GPVI-specific ligands. This may reflect a role for co-receptors in the response to collagen.

AB - The major activation-inducing collagen receptor glycoprotein VI (GPVI) has been cloned within the last two years. It is a member of the Ig superfamily of proteins and is constitutively associated with the ITAM-bearing Fc receptor gamma-chain (FcR gamma-chain). GPVI signals through a pathway that involves several of the proteins used by Fc, B- and T-lymphocyte receptors and which takes place in glycolipid-enriched membrane domains in the plasma membrane known as GEMs. Responses to GPVI are regulated by PECAM-1 (CD31) and possibly other ITIM-bearing receptors. Despite a pivotal role for GPVI, there are important differences between signalling events to collagen and GPVI-specific ligands. This may reflect a role for co-receptors in the response to collagen.

M3 - Review article

C2 - 11487016

VL - 86

SP - 276

EP - 288

JO - Journal of Thrombosis and Haemostasis

JF - Journal of Thrombosis and Haemostasis

SN - 1538-7933

IS - 1

ER -