The relation of object naming and other visual speech production tasks : a large scale voxel-based morphometric study

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@article{efa0ba2738434b03b9d1cd2736c0d239,
title = "The relation of object naming and other visual speech production tasks : a large scale voxel-based morphometric study",
abstract = "We report a lesion–symptom mapping analysis of visual speech production deficits in a large group (280) of stroke patients at the sub-acute stage (<120 days post-stroke). Performance on object naming was evaluated alongside three other tests of visual speech production, namely sentence production to a picture, sentence reading and nonword reading. A principal component analysis was performed on all these tests' scores and revealed a {\textquoteleft}shared{\textquoteright} component that loaded across all the visual speech production tasks and a {\textquoteleft}unique{\textquoteright} component that isolated object naming from the other three tasks. Regions for the shared component were observed in the left fronto-temporal cortices, fusiform gyrus and bilateral visual cortices. Lesions in these regions linked to both poor object naming and impairment in general visual–speech production. On the other hand, the unique naming component was potentially associated with the bilateral anterior temporal poles, hippocampus and cerebellar areas. This is in line with the models proposing that object naming relies on a left-lateralised language dominant system that interacts with a bilateral anterior temporal network. Neuropsychological deficits in object naming can reflect both the increased demands specific to the task and the more general difficulties in language processing.",
keywords = "Stroke, Principal component analysis, VBM, Picture naming, Speech production, Sentence reading, Nonword reading, Sentence production, Picture description, BCoS, CT",
author = "Lau, {Johnny King L.} and Humphreys, {Glyn W.} and Hassan Douis and Alex Balani and Wai-ling Bickerton and Pia Rotshtein",
year = "2015",
doi = "10.1016/j.nicl.2015.01.015",
language = "English",
volume = "7",
pages = "463--475",
journal = "NeuroImage: Clinical",
issn = "2213-1582",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - The relation of object naming and other visual speech production tasks : a large scale voxel-based morphometric study

AU - Lau, Johnny King L.

AU - Humphreys, Glyn W.

AU - Douis, Hassan

AU - Balani, Alex

AU - Bickerton, Wai-ling

AU - Rotshtein, Pia

PY - 2015

Y1 - 2015

N2 - We report a lesion–symptom mapping analysis of visual speech production deficits in a large group (280) of stroke patients at the sub-acute stage (<120 days post-stroke). Performance on object naming was evaluated alongside three other tests of visual speech production, namely sentence production to a picture, sentence reading and nonword reading. A principal component analysis was performed on all these tests' scores and revealed a ‘shared’ component that loaded across all the visual speech production tasks and a ‘unique’ component that isolated object naming from the other three tasks. Regions for the shared component were observed in the left fronto-temporal cortices, fusiform gyrus and bilateral visual cortices. Lesions in these regions linked to both poor object naming and impairment in general visual–speech production. On the other hand, the unique naming component was potentially associated with the bilateral anterior temporal poles, hippocampus and cerebellar areas. This is in line with the models proposing that object naming relies on a left-lateralised language dominant system that interacts with a bilateral anterior temporal network. Neuropsychological deficits in object naming can reflect both the increased demands specific to the task and the more general difficulties in language processing.

AB - We report a lesion–symptom mapping analysis of visual speech production deficits in a large group (280) of stroke patients at the sub-acute stage (<120 days post-stroke). Performance on object naming was evaluated alongside three other tests of visual speech production, namely sentence production to a picture, sentence reading and nonword reading. A principal component analysis was performed on all these tests' scores and revealed a ‘shared’ component that loaded across all the visual speech production tasks and a ‘unique’ component that isolated object naming from the other three tasks. Regions for the shared component were observed in the left fronto-temporal cortices, fusiform gyrus and bilateral visual cortices. Lesions in these regions linked to both poor object naming and impairment in general visual–speech production. On the other hand, the unique naming component was potentially associated with the bilateral anterior temporal poles, hippocampus and cerebellar areas. This is in line with the models proposing that object naming relies on a left-lateralised language dominant system that interacts with a bilateral anterior temporal network. Neuropsychological deficits in object naming can reflect both the increased demands specific to the task and the more general difficulties in language processing.

KW - Stroke

KW - Principal component analysis

KW - VBM

KW - Picture naming

KW - Speech production

KW - Sentence reading

KW - Nonword reading

KW - Sentence production

KW - Picture description

KW - BCoS

KW - CT

U2 - 10.1016/j.nicl.2015.01.015

DO - 10.1016/j.nicl.2015.01.015

M3 - Article

C2 - 25685713

VL - 7

SP - 463

EP - 475

JO - NeuroImage: Clinical

JF - NeuroImage: Clinical

SN - 2213-1582

ER -