The Prevalence and Phenomenology of Repetitive Behavior in Genetic Syndromes

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The Prevalence and Phenomenology of Repetitive Behavior in Genetic Syndromes. / Moss, J; Oliver, Christopher; Arron, Kate; Burbidge, C; Berg, K.

In: Journal of Autism and Developmental Disorders, Vol. 39, No. 4, 27.11.2008, p. 572-588.

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@article{731c55ab62c54aee9af90d43b63e211b,
title = "The Prevalence and Phenomenology of Repetitive Behavior in Genetic Syndromes",
abstract = "We investigated the prevalence and phenomenology of repetitive behavior in genetic syndromes to detail profiles of behavior. The Repetitive Behaviour Questionnaire (RBQ) provides fine-grained identification of repetitive behaviors. The RBQ was employed to examine repetitive behavior in Angelman (N = 104), Cornelia de Lange (N = 101), Cri-du-Chat (N = 58), Fragile X (N = 191), Prader-Willi (N = 189), Lowe (N = 56) and Smith-Magenis (N = 42) syndromes and individuals with intellectual disability of heterogeneous aetiology (N = 56). Repetitive behavior was variable across syndromes. Fragile X syndrome scored highly on all subscales. Angelman syndrome demonstrated a significantly lowered probability for most behaviors. Prader-Willi, Cri-du-Chat and Smith-Magenis syndrome evidenced unique profiles of repetitive behavior. There is extreme heterogeneity of repetitive behavior across genetic syndromes, highlighting syndrome specific profiles.",
keywords = "Compulsive behavior, Behavioral phenotype, Repetitive behavior, Autism spectrum disorder, Stereotyped behavior",
author = "J Moss and Christopher Oliver and Kate Arron and C Burbidge and K Berg",
year = "2008",
month = "11",
day = "27",
doi = "10.1007/s10803-008-0655-6",
language = "English",
volume = "39",
pages = "572--588",
journal = "Journal of Autism and Developmental Disorders",
issn = "0162-3257",
publisher = "Springer",
number = "4",

}

RIS

TY - JOUR

T1 - The Prevalence and Phenomenology of Repetitive Behavior in Genetic Syndromes

AU - Moss, J

AU - Oliver, Christopher

AU - Arron, Kate

AU - Burbidge, C

AU - Berg, K

PY - 2008/11/27

Y1 - 2008/11/27

N2 - We investigated the prevalence and phenomenology of repetitive behavior in genetic syndromes to detail profiles of behavior. The Repetitive Behaviour Questionnaire (RBQ) provides fine-grained identification of repetitive behaviors. The RBQ was employed to examine repetitive behavior in Angelman (N = 104), Cornelia de Lange (N = 101), Cri-du-Chat (N = 58), Fragile X (N = 191), Prader-Willi (N = 189), Lowe (N = 56) and Smith-Magenis (N = 42) syndromes and individuals with intellectual disability of heterogeneous aetiology (N = 56). Repetitive behavior was variable across syndromes. Fragile X syndrome scored highly on all subscales. Angelman syndrome demonstrated a significantly lowered probability for most behaviors. Prader-Willi, Cri-du-Chat and Smith-Magenis syndrome evidenced unique profiles of repetitive behavior. There is extreme heterogeneity of repetitive behavior across genetic syndromes, highlighting syndrome specific profiles.

AB - We investigated the prevalence and phenomenology of repetitive behavior in genetic syndromes to detail profiles of behavior. The Repetitive Behaviour Questionnaire (RBQ) provides fine-grained identification of repetitive behaviors. The RBQ was employed to examine repetitive behavior in Angelman (N = 104), Cornelia de Lange (N = 101), Cri-du-Chat (N = 58), Fragile X (N = 191), Prader-Willi (N = 189), Lowe (N = 56) and Smith-Magenis (N = 42) syndromes and individuals with intellectual disability of heterogeneous aetiology (N = 56). Repetitive behavior was variable across syndromes. Fragile X syndrome scored highly on all subscales. Angelman syndrome demonstrated a significantly lowered probability for most behaviors. Prader-Willi, Cri-du-Chat and Smith-Magenis syndrome evidenced unique profiles of repetitive behavior. There is extreme heterogeneity of repetitive behavior across genetic syndromes, highlighting syndrome specific profiles.

KW - Compulsive behavior

KW - Behavioral phenotype

KW - Repetitive behavior

KW - Autism spectrum disorder

KW - Stereotyped behavior

U2 - 10.1007/s10803-008-0655-6

DO - 10.1007/s10803-008-0655-6

M3 - Article

VL - 39

SP - 572

EP - 588

JO - Journal of Autism and Developmental Disorders

JF - Journal of Autism and Developmental Disorders

SN - 0162-3257

IS - 4

ER -