Abstract
Self-injurious and aggressive behaviors are common in fragile X syndrome (FXS). However, little is known about the persistence of these behaviors and associated risk markers. We established the prevalence and persistence of self-injurious and aggressive behaviors over eight years in males with FXS, and associations with risk markers. Results showed 77% and 69% persistence rates for self-injurious and aggressive behavior, respectively. Baseline levels of repetitive behavior predicted persistent self-injurious behavior. Chronological age, impulsivity and overactivity were associated with persistent aggressive behavior but only impulsivity predicted persistence. This is the first study to document the persistence of self-injurious and aggressive behavior in FXS over the medium to long term and to identify behavioral risk markers that might facilitate targeted early intervention.
Original language | English |
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Pages (from-to) | 2913-2922 |
Number of pages | 10 |
Journal | Journal of Autism and Developmental Disorders |
Volume | 49 |
Issue number | 7 |
Early online date | 24 Apr 2019 |
DOIs | |
Publication status | Published - 15 Jul 2019 |
Keywords
- Aggression
- Autism
- Challenging behavior
- Early intervention
- Fragile X syndrome
- Impulsivity
- Repetitive behavior
- Risk markers
- Self-injurious behavior
ASJC Scopus subject areas
- Developmental and Educational Psychology