The persistence of self-injurious and aggressive behavior in males with fragile X syndrome over 8 years: a longitudinal study of prevalence and predictive risk markers
Research output: Contribution to journal › Article
Colleges, School and Institutes
- Centre for Innovative Research Across the Life Course, Coventry University, Coventry, UK.
- Cerebra Centre for Neurodevelopmental Disorders, School of Psychology, University of Birmingham, 52 Pritchatts Road, Birmingham, B15 2TT, UK.
- Department of Psychology, University of Wolverhampton, Wolverhampton, UK.
- Cerebra Centre for Neurodevelopmental Disorders, School of Psychology, University of Birmingham, 52 Pritchatts Road, Birmingham, B15 2TT, UK. firstname.lastname@example.org.
Self-injurious and aggressive behaviors are common in fragile X syndrome (FXS). However, little is known about the persistence of these behaviors and associated risk markers. We established the prevalence and persistence of self-injurious and aggressive behaviors over eight years in males with FXS, and associations with risk markers. Results showed 77% and 69% persistence rates for self-injurious and aggressive behavior, respectively. Baseline levels of repetitive behavior predicted persistent self-injurious behavior. Chronological age, impulsivity and overactivity were associated with persistent aggressive behavior but only impulsivity predicted persistence. This is the first study to document the persistence of self-injurious and aggressive behavior in FXS over the medium to long term and to identify behavioral risk markers that might facilitate targeted early intervention.
|Number of pages||10|
|Journal||Journal of Autism and Developmental Disorders|
|Early online date||24 Apr 2019|
|Publication status||E-pub ahead of print - 24 Apr 2019|
- Aggression, Autism, Challenging behavior, Early intervention, Fragile X syndrome, Impulsivity, Repetitive behavior, Risk markers, Self-injurious behavior