The periodontal health component of the Renal Impairment In Secondary Care (RIISC) cohort study: a description of the rationale, methodology and initial baseline results

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The periodontal health component of the Renal Impairment In Secondary Care (RIISC) cohort study : a description of the rationale, methodology and initial baseline results. / Sharma, Praveen; Dietrich, Thomas; Sidhu, Amneet; Vithlani, Viren; Rahman, Mutahir; Stringer, Stephanie; Jesky, Mark; Kaur, Okdeep; Ferro, Charles; Cockwell, Paul; Chapple, Iain L C.

In: Journal of Clinical Periodontology, Vol. 41, No. 7, 07.2014, p. 653-61.

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@article{a75786ba8be246379f6734ead8e33594,
title = "The periodontal health component of the Renal Impairment In Secondary Care (RIISC) cohort study: a description of the rationale, methodology and initial baseline results",
abstract = "INTRODUCTION: Chronic kidney disease (CKD) is associated with significant morbidity and mortality. There is a need to identify novel and modifiable risk factors in such patients. The periodontal component of the Renal Impairment In Secondary Care (RIISC) study aims to evaluate the association between chronic periodontitis and CKD progression.METHODS: The RIISC study is a prospective, observational cohort study of patients with CKD from a renal clinic at a hospital in the West Midlands region of the UK. Patients undergo a periodontal examination and plaque and saliva sampling. To benchmark the oral health status of the RIISC cohort, we compared it to the Adult Dental Health Survey 2009 (ADHS), a representative survey of the oral health of community dwelling adults in the UK.RESULTS: Of the first 500 patients recruited into the RIISC study, 469 patients underwent a dental examination and 80 (17%) were edentulous. Among dentate subjects, patients within RIISC were significantly more likely to have any (OR 4.0 95% CI 2.7-5.9) or severe (OR 3.8 95% CI 2.5-5.6) periodontitis compared to the ADHS sample.CONCLUSION: The prevalence and severity of chronic periodontitis in this cohort of CKD patients is markedly higher than a geographically matched control population.",
keywords = "Adult, Aged, Aged, 80 and over, Case-Control Studies, Chronic Periodontitis, Cohort Studies, Dental Plaque, Dental Plaque Index, England, Female, Health Status, Humans, Male, Middle Aged, Mouth, Edentulous, Oral Health, Periodontal Attachment Loss, Periodontal Index, Periodontal Pocket, Prevalence, Prospective Studies, Renal Insufficiency, Chronic, Saliva, Vulnerable Populations, Young Adult",
author = "Praveen Sharma and Thomas Dietrich and Amneet Sidhu and Viren Vithlani and Mutahir Rahman and Stephanie Stringer and Mark Jesky and Okdeep Kaur and Charles Ferro and Paul Cockwell and Chapple, {Iain L C}",
note = "{\textcopyright} 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.",
year = "2014",
month = jul,
doi = "10.1111/jcpe.12263",
language = "English",
volume = "41",
pages = "653--61",
journal = "Journal of Clinical Periodontology",
issn = "0303-6979",
publisher = "Wiley",
number = "7",

}

RIS

TY - JOUR

T1 - The periodontal health component of the Renal Impairment In Secondary Care (RIISC) cohort study

T2 - a description of the rationale, methodology and initial baseline results

AU - Sharma, Praveen

AU - Dietrich, Thomas

AU - Sidhu, Amneet

AU - Vithlani, Viren

AU - Rahman, Mutahir

AU - Stringer, Stephanie

AU - Jesky, Mark

AU - Kaur, Okdeep

AU - Ferro, Charles

AU - Cockwell, Paul

AU - Chapple, Iain L C

N1 - © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

PY - 2014/7

Y1 - 2014/7

N2 - INTRODUCTION: Chronic kidney disease (CKD) is associated with significant morbidity and mortality. There is a need to identify novel and modifiable risk factors in such patients. The periodontal component of the Renal Impairment In Secondary Care (RIISC) study aims to evaluate the association between chronic periodontitis and CKD progression.METHODS: The RIISC study is a prospective, observational cohort study of patients with CKD from a renal clinic at a hospital in the West Midlands region of the UK. Patients undergo a periodontal examination and plaque and saliva sampling. To benchmark the oral health status of the RIISC cohort, we compared it to the Adult Dental Health Survey 2009 (ADHS), a representative survey of the oral health of community dwelling adults in the UK.RESULTS: Of the first 500 patients recruited into the RIISC study, 469 patients underwent a dental examination and 80 (17%) were edentulous. Among dentate subjects, patients within RIISC were significantly more likely to have any (OR 4.0 95% CI 2.7-5.9) or severe (OR 3.8 95% CI 2.5-5.6) periodontitis compared to the ADHS sample.CONCLUSION: The prevalence and severity of chronic periodontitis in this cohort of CKD patients is markedly higher than a geographically matched control population.

AB - INTRODUCTION: Chronic kidney disease (CKD) is associated with significant morbidity and mortality. There is a need to identify novel and modifiable risk factors in such patients. The periodontal component of the Renal Impairment In Secondary Care (RIISC) study aims to evaluate the association between chronic periodontitis and CKD progression.METHODS: The RIISC study is a prospective, observational cohort study of patients with CKD from a renal clinic at a hospital in the West Midlands region of the UK. Patients undergo a periodontal examination and plaque and saliva sampling. To benchmark the oral health status of the RIISC cohort, we compared it to the Adult Dental Health Survey 2009 (ADHS), a representative survey of the oral health of community dwelling adults in the UK.RESULTS: Of the first 500 patients recruited into the RIISC study, 469 patients underwent a dental examination and 80 (17%) were edentulous. Among dentate subjects, patients within RIISC were significantly more likely to have any (OR 4.0 95% CI 2.7-5.9) or severe (OR 3.8 95% CI 2.5-5.6) periodontitis compared to the ADHS sample.CONCLUSION: The prevalence and severity of chronic periodontitis in this cohort of CKD patients is markedly higher than a geographically matched control population.

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Case-Control Studies

KW - Chronic Periodontitis

KW - Cohort Studies

KW - Dental Plaque

KW - Dental Plaque Index

KW - England

KW - Female

KW - Health Status

KW - Humans

KW - Male

KW - Middle Aged

KW - Mouth, Edentulous

KW - Oral Health

KW - Periodontal Attachment Loss

KW - Periodontal Index

KW - Periodontal Pocket

KW - Prevalence

KW - Prospective Studies

KW - Renal Insufficiency, Chronic

KW - Saliva

KW - Vulnerable Populations

KW - Young Adult

U2 - 10.1111/jcpe.12263

DO - 10.1111/jcpe.12263

M3 - Article

C2 - 24738870

VL - 41

SP - 653

EP - 661

JO - Journal of Clinical Periodontology

JF - Journal of Clinical Periodontology

SN - 0303-6979

IS - 7

ER -