The PanCareSurFup consortium: research and guidelines to improve lives for survivors of childhood cancer

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The PanCareSurFup consortium : research and guidelines to improve lives for survivors of childhood cancer. / Byrne, Julianne; Alessi, Daniela; Allodji, Rodrigue S; Bagnasco, Francesca; Bárdi, Edit; Bautz, Andrea; Bright, Chloe J; Brown, Morven; Diallo, Ibrahima; Feijen, Elizabeth A M Lieke; Fidler, Miranda M; Frey, Eva; Garwicz, Stanislaw; Grabow, Desiree; Gudmundsdottir, Thorgerdur; Hagberg, Oskar; Harila-Saari, Arja; Hau, Eva M; Haupt, Riccardo; Hawkins, Mike M; Jakab, Zsuzsanna; Jankovic, Momcilo; Kaatsch, Peter; Kaiser, Melanie; Kremer, Leontien C M; Kuehni, Claudia E; Kuonen, Rahel; Ladenstein, Ruth; Lähteenmäki, Päivi Maria; Levitt, Gill; Linge, Helena; LLanas, Damien; Michel, Gisela; Morsellino, Vera; Mulder, Renee L; Reulen, Raoul C; Ronckers, Cécile M; Sacerdote, Carlotta; Skinner, Roderick; Steliarova-Foucher, Eva; van der Pal, Helena J; de Vathaire, Florent; Vũ Bezin, Giao; Wesenberg, Finn; Wiebe, Thomas; Winter, David L; Falck Winther, Jeanette; Witthoff, Elise; Zadravec Zaletel, Lorna; Hjorth, Lars.

In: European Journal of Cancer, Vol. 103, 11.2018, p. 238-248.

Research output: Contribution to journalArticle

Harvard

Byrne, J, Alessi, D, Allodji, RS, Bagnasco, F, Bárdi, E, Bautz, A, Bright, CJ, Brown, M, Diallo, I, Feijen, EAML, Fidler, MM, Frey, E, Garwicz, S, Grabow, D, Gudmundsdottir, T, Hagberg, O, Harila-Saari, A, Hau, EM, Haupt, R, Hawkins, MM, Jakab, Z, Jankovic, M, Kaatsch, P, Kaiser, M, Kremer, LCM, Kuehni, CE, Kuonen, R, Ladenstein, R, Lähteenmäki, PM, Levitt, G, Linge, H, LLanas, D, Michel, G, Morsellino, V, Mulder, RL, Reulen, RC, Ronckers, CM, Sacerdote, C, Skinner, R, Steliarova-Foucher, E, van der Pal, HJ, de Vathaire, F, Vũ Bezin, G, Wesenberg, F, Wiebe, T, Winter, DL, Falck Winther, J, Witthoff, E, Zadravec Zaletel, L & Hjorth, L 2018, 'The PanCareSurFup consortium: research and guidelines to improve lives for survivors of childhood cancer', European Journal of Cancer, vol. 103, pp. 238-248. https://doi.org/10.1016/j.ejca.2018.08.017

APA

Byrne, J., Alessi, D., Allodji, R. S., Bagnasco, F., Bárdi, E., Bautz, A., Bright, C. J., Brown, M., Diallo, I., Feijen, E. A. M. L., Fidler, M. M., Frey, E., Garwicz, S., Grabow, D., Gudmundsdottir, T., Hagberg, O., Harila-Saari, A., Hau, E. M., Haupt, R., ... Hjorth, L. (2018). The PanCareSurFup consortium: research and guidelines to improve lives for survivors of childhood cancer. European Journal of Cancer, 103, 238-248. https://doi.org/10.1016/j.ejca.2018.08.017

Vancouver

Author

Byrne, Julianne ; Alessi, Daniela ; Allodji, Rodrigue S ; Bagnasco, Francesca ; Bárdi, Edit ; Bautz, Andrea ; Bright, Chloe J ; Brown, Morven ; Diallo, Ibrahima ; Feijen, Elizabeth A M Lieke ; Fidler, Miranda M ; Frey, Eva ; Garwicz, Stanislaw ; Grabow, Desiree ; Gudmundsdottir, Thorgerdur ; Hagberg, Oskar ; Harila-Saari, Arja ; Hau, Eva M ; Haupt, Riccardo ; Hawkins, Mike M ; Jakab, Zsuzsanna ; Jankovic, Momcilo ; Kaatsch, Peter ; Kaiser, Melanie ; Kremer, Leontien C M ; Kuehni, Claudia E ; Kuonen, Rahel ; Ladenstein, Ruth ; Lähteenmäki, Päivi Maria ; Levitt, Gill ; Linge, Helena ; LLanas, Damien ; Michel, Gisela ; Morsellino, Vera ; Mulder, Renee L ; Reulen, Raoul C ; Ronckers, Cécile M ; Sacerdote, Carlotta ; Skinner, Roderick ; Steliarova-Foucher, Eva ; van der Pal, Helena J ; de Vathaire, Florent ; Vũ Bezin, Giao ; Wesenberg, Finn ; Wiebe, Thomas ; Winter, David L ; Falck Winther, Jeanette ; Witthoff, Elise ; Zadravec Zaletel, Lorna ; Hjorth, Lars. / The PanCareSurFup consortium : research and guidelines to improve lives for survivors of childhood cancer. In: European Journal of Cancer. 2018 ; Vol. 103. pp. 238-248.

Bibtex

@article{a720a7d0cd2140bf9740bec48cbb621b,
title = "The PanCareSurFup consortium: research and guidelines to improve lives for survivors of childhood cancer",
abstract = "BACKGROUND: Second malignant neoplasms and cardiotoxicity are among the most serious and frequent adverse health outcomes experienced by childhood and adolescent cancer survivors (CCSs) and contribute significantly to their increased risk of premature mortality. Owing to differences in health-care systems, language and culture across the continent, Europe has had limited success in establishing multi-country collaborations needed to assemble the numbers of survivors required to clarify the health issues arising after successful cancer treatment. PanCareSurFup (PCSF) is the first pan-European project to evaluate some of the serious long-term health risks faced by survivors. This article sets out the overall rationale, methods and preliminary results of PCSF.METHODS: The PCSF consortium pooled data from 13 cancer registries and hospitals in 12 European countries to evaluate subsequent primary malignancies, cardiac disease and late mortality in survivors diagnosed between ages 0 and 20 years. In addition, PCSF integrated radiation dosimetry to sites of second malignancies and to the heart, developed evidence-based guidelines for long-term care and for transition services, and disseminated results to survivors and the public.RESULTS: We identified 115,596 individuals diagnosed with cancer, of whom 83,333 were 5-year survivors and diagnosed from 1940 to 2011. This single data set forms the basis for cohort analyses of subsequent malignancies, cardiac disease and late mortality and case-control studies of subsequent malignancies and cardiac disease in 5-year survivors.CONCLUSIONS: PCSF delivered specific estimates of risk and comprehensive guidelines to help survivors and care-givers. The expected benefit is to provide every European CCS with improved access to care and better long-term health.",
author = "Julianne Byrne and Daniela Alessi and Allodji, {Rodrigue S} and Francesca Bagnasco and Edit B{\'a}rdi and Andrea Bautz and Bright, {Chloe J} and Morven Brown and Ibrahima Diallo and Feijen, {Elizabeth A M Lieke} and Fidler, {Miranda M} and Eva Frey and Stanislaw Garwicz and Desiree Grabow and Thorgerdur Gudmundsdottir and Oskar Hagberg and Arja Harila-Saari and Hau, {Eva M} and Riccardo Haupt and Hawkins, {Mike M} and Zsuzsanna Jakab and Momcilo Jankovic and Peter Kaatsch and Melanie Kaiser and Kremer, {Leontien C M} and Kuehni, {Claudia E} and Rahel Kuonen and Ruth Ladenstein and L{\"a}hteenm{\"a}ki, {P{\"a}ivi Maria} and Gill Levitt and Helena Linge and Damien LLanas and Gisela Michel and Vera Morsellino and Mulder, {Renee L} and Reulen, {Raoul C} and Ronckers, {C{\'e}cile M} and Carlotta Sacerdote and Roderick Skinner and Eva Steliarova-Foucher and {van der Pal}, {Helena J} and {de Vathaire}, Florent and {Vũ Bezin}, Giao and Finn Wesenberg and Thomas Wiebe and Winter, {David L} and {Falck Winther}, Jeanette and Elise Witthoff and {Zadravec Zaletel}, Lorna and Lars Hjorth",
note = "Copyright {\textcopyright} 2018 Elsevier Ltd. All rights reserved.",
year = "2018",
month = nov
doi = "10.1016/j.ejca.2018.08.017",
language = "English",
volume = "103",
pages = "238--248",
journal = "European Journal of Cancer",
issn = "0959-8049",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - The PanCareSurFup consortium

T2 - research and guidelines to improve lives for survivors of childhood cancer

AU - Byrne, Julianne

AU - Alessi, Daniela

AU - Allodji, Rodrigue S

AU - Bagnasco, Francesca

AU - Bárdi, Edit

AU - Bautz, Andrea

AU - Bright, Chloe J

AU - Brown, Morven

AU - Diallo, Ibrahima

AU - Feijen, Elizabeth A M Lieke

AU - Fidler, Miranda M

AU - Frey, Eva

AU - Garwicz, Stanislaw

AU - Grabow, Desiree

AU - Gudmundsdottir, Thorgerdur

AU - Hagberg, Oskar

AU - Harila-Saari, Arja

AU - Hau, Eva M

AU - Haupt, Riccardo

AU - Hawkins, Mike M

AU - Jakab, Zsuzsanna

AU - Jankovic, Momcilo

AU - Kaatsch, Peter

AU - Kaiser, Melanie

AU - Kremer, Leontien C M

AU - Kuehni, Claudia E

AU - Kuonen, Rahel

AU - Ladenstein, Ruth

AU - Lähteenmäki, Päivi Maria

AU - Levitt, Gill

AU - Linge, Helena

AU - LLanas, Damien

AU - Michel, Gisela

AU - Morsellino, Vera

AU - Mulder, Renee L

AU - Reulen, Raoul C

AU - Ronckers, Cécile M

AU - Sacerdote, Carlotta

AU - Skinner, Roderick

AU - Steliarova-Foucher, Eva

AU - van der Pal, Helena J

AU - de Vathaire, Florent

AU - Vũ Bezin, Giao

AU - Wesenberg, Finn

AU - Wiebe, Thomas

AU - Winter, David L

AU - Falck Winther, Jeanette

AU - Witthoff, Elise

AU - Zadravec Zaletel, Lorna

AU - Hjorth, Lars

N1 - Copyright © 2018 Elsevier Ltd. All rights reserved.

PY - 2018/11

Y1 - 2018/11

N2 - BACKGROUND: Second malignant neoplasms and cardiotoxicity are among the most serious and frequent adverse health outcomes experienced by childhood and adolescent cancer survivors (CCSs) and contribute significantly to their increased risk of premature mortality. Owing to differences in health-care systems, language and culture across the continent, Europe has had limited success in establishing multi-country collaborations needed to assemble the numbers of survivors required to clarify the health issues arising after successful cancer treatment. PanCareSurFup (PCSF) is the first pan-European project to evaluate some of the serious long-term health risks faced by survivors. This article sets out the overall rationale, methods and preliminary results of PCSF.METHODS: The PCSF consortium pooled data from 13 cancer registries and hospitals in 12 European countries to evaluate subsequent primary malignancies, cardiac disease and late mortality in survivors diagnosed between ages 0 and 20 years. In addition, PCSF integrated radiation dosimetry to sites of second malignancies and to the heart, developed evidence-based guidelines for long-term care and for transition services, and disseminated results to survivors and the public.RESULTS: We identified 115,596 individuals diagnosed with cancer, of whom 83,333 were 5-year survivors and diagnosed from 1940 to 2011. This single data set forms the basis for cohort analyses of subsequent malignancies, cardiac disease and late mortality and case-control studies of subsequent malignancies and cardiac disease in 5-year survivors.CONCLUSIONS: PCSF delivered specific estimates of risk and comprehensive guidelines to help survivors and care-givers. The expected benefit is to provide every European CCS with improved access to care and better long-term health.

AB - BACKGROUND: Second malignant neoplasms and cardiotoxicity are among the most serious and frequent adverse health outcomes experienced by childhood and adolescent cancer survivors (CCSs) and contribute significantly to their increased risk of premature mortality. Owing to differences in health-care systems, language and culture across the continent, Europe has had limited success in establishing multi-country collaborations needed to assemble the numbers of survivors required to clarify the health issues arising after successful cancer treatment. PanCareSurFup (PCSF) is the first pan-European project to evaluate some of the serious long-term health risks faced by survivors. This article sets out the overall rationale, methods and preliminary results of PCSF.METHODS: The PCSF consortium pooled data from 13 cancer registries and hospitals in 12 European countries to evaluate subsequent primary malignancies, cardiac disease and late mortality in survivors diagnosed between ages 0 and 20 years. In addition, PCSF integrated radiation dosimetry to sites of second malignancies and to the heart, developed evidence-based guidelines for long-term care and for transition services, and disseminated results to survivors and the public.RESULTS: We identified 115,596 individuals diagnosed with cancer, of whom 83,333 were 5-year survivors and diagnosed from 1940 to 2011. This single data set forms the basis for cohort analyses of subsequent malignancies, cardiac disease and late mortality and case-control studies of subsequent malignancies and cardiac disease in 5-year survivors.CONCLUSIONS: PCSF delivered specific estimates of risk and comprehensive guidelines to help survivors and care-givers. The expected benefit is to provide every European CCS with improved access to care and better long-term health.

U2 - 10.1016/j.ejca.2018.08.017

DO - 10.1016/j.ejca.2018.08.017

M3 - Article

C2 - 30286417

VL - 103

SP - 238

EP - 248

JO - European Journal of Cancer

JF - European Journal of Cancer

SN - 0959-8049

ER -