Abstract
Two inbred strains of mice C3H/HE and SWR, and generations produced by intercrossing, were studied to investigate the effect of heredity on muscle composition. The data were found to be consistent with a polygenic mode of inheritance. No simple effect of sex-linkage or maternal influence was evident. The heritability of fibre type percentage total fibre number and the relative size of Type I and Type II fibres were highly significant. Principal component analysis yielded a "genetic" vector which accounted for 57% of the variation in muscle fibre composition. Patterns of covariance of fibre type percentage, total fibre number and relative sizes of Type I and Type II fibres showed a single correlated response.
| Original language | English |
|---|---|
| Pages (from-to) | 109-15 |
| Number of pages | 7 |
| Journal | Comparative Biochemistry and Physiology. A. Comparative Physiology |
| Volume | 81 |
| Issue number | 1 |
| Publication status | Published - 1985 |
Keywords
- Animals
- Body Composition
- Crosses, Genetic
- Female
- Male
- Mice
- Mice, Inbred C3H
- Mice, Inbred Strains
- Muscles
- Species Specificity