The influence of surface treatment by hydrogenation on the biocompatibility of different hydroxyapatite materials

Research output: Contribution to journalConference article


  • E Palcevskis
  • A Dindune
  • Y Dekhtyar
  • N Polyaka
  • D Veljović

Colleges, School and Institutes


The influence of hydrogenation on the biocompatibility of different hydroxyapatite (HAP) materials was tested. Materials consisted of pure HAP, HAP substituted with manganese (Mn+2) and with magnesium (Mg+2) - all axially pressed and conventionally sintered for 2 h at 1200 deg. C; pure HAP isostatic pressed and sintered by a microwave technique for 15 min at temperature of 1200 deg. C. Biocompatibility was compared by enumeration of the number of osteoblast-like cells to the materials before and after hydrogenation. Obtained results show that the osteoblastic cells demonstrated a higher ability to attach to HAP if its surface was negatively charged. Hydrogenation altered the surface potential; HAP substituted with manganese - HAP(Mn) and with magnesium - HAP(Mg) demonstrated the highest ability to engineer the charge


Original languageEnglish
Article number012032
Number of pages6
JournalIOP Conference Series: Materials Science and Engineering
Issue number1
Publication statusPublished - 23 Jun 2011
EventAnnual Conference on Functional Materials and Nanotechnologies - Riga, Latvia
Duration: 5 Apr 20118 Apr 2011