The impact of acute and chronic catecholamines on respiratory responses to hypoxic stress in the rat

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Chronic catecholamine production is associated with desensitisation and down-regulation of adrenergic receptors and occurs in conditions, such as heart failure and myocardial infarction. The effects of further acute adrenergic stimulation, which may occur during exercise, and their subsequent effects on chemosensitivity and ventilation are unclear. Chronic isoprenaline (ISO) increased ventilation by 50 % (P 


Original languageEnglish
Pages (from-to)209-219
Number of pages11
JournalPfluegers Archiv: European journal of physiology
Issue number2
Publication statusPublished - 2013