The HLA association with Graves' disease is sex-specific in Hong Kong Chinese subjects

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  • D A Cavan
  • M A Penny
  • D Jenkins
  • C Chow
  • C S Cockram
  • B R Hawkins

Colleges, School and Institutes


Graves' disease is associated with different HLA genes in Caucasians and the Chinese, in whom the HLA associations may be stronger in males than females. Common HLA-associated susceptibility in both races may occur at the HLA-DQ loci. The aims of this study were to examine the HLA-A, B, DR and DQ associations with Graves' disease in a Hong Kong Chinese population and to determine whether the HLA associations differ between the sexes and between subjects with and without thyrotoxic periodic paralysis.


Original languageEnglish
Pages (from-to)63-6
Number of pages4
JournalClinical Endocrinology
Issue number1
Publication statusPublished - 1994