The genetics of chronic obstructive pulmonary disease

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The genetics of chronic obstructive pulmonary disease. / Turner, Alice; Stockley, Robert.

In: Respiratory research, Vol. 7, 20.10.2006, p. 130.

Research output: Contribution to journalReview articlepeer-review

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@article{e6a70aab01bc4722a90dc24c4ba5b579,
title = "The genetics of chronic obstructive pulmonary disease",
abstract = "Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease caused by the interaction of genetic susceptibility and environmental influences. There is increasing evidence that genes link to disease pathogenesis and heterogeneity by causing variation in protease anti-protease systems, defence against oxidative stress and inflammation. The main methods of genomic research for complex disease traits are described, together with the genes implicated in COPD thus far, their roles in disease causation and the future for this area of investigation.",
author = "Alice Turner and Robert Stockley",
year = "2006",
month = oct,
day = "20",
doi = "10.1186/1465-9921-7-130",
language = "English",
volume = "7",
pages = "130",
journal = "Respiratory research",
issn = "1465-9921",
publisher = "Springer",

}

RIS

TY - JOUR

T1 - The genetics of chronic obstructive pulmonary disease

AU - Turner, Alice

AU - Stockley, Robert

PY - 2006/10/20

Y1 - 2006/10/20

N2 - Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease caused by the interaction of genetic susceptibility and environmental influences. There is increasing evidence that genes link to disease pathogenesis and heterogeneity by causing variation in protease anti-protease systems, defence against oxidative stress and inflammation. The main methods of genomic research for complex disease traits are described, together with the genes implicated in COPD thus far, their roles in disease causation and the future for this area of investigation.

AB - Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease caused by the interaction of genetic susceptibility and environmental influences. There is increasing evidence that genes link to disease pathogenesis and heterogeneity by causing variation in protease anti-protease systems, defence against oxidative stress and inflammation. The main methods of genomic research for complex disease traits are described, together with the genes implicated in COPD thus far, their roles in disease causation and the future for this area of investigation.

U2 - 10.1186/1465-9921-7-130

DO - 10.1186/1465-9921-7-130

M3 - Review article

C2 - 17054776

VL - 7

SP - 130

JO - Respiratory research

JF - Respiratory research

SN - 1465-9921

ER -