The evolving role of cardiac magnetic resonance in primary mitral regurgitation: ready for prime time?

Research output: Contribution to journalArticlepeer-review


Colleges, School and Institutes

External organisations

  • Department of Cardiology, University Hospital Birmingham and Institute of Cardiovascular Science, University of Birmingham, Edgbaston, Birmingham, UK.
  • CMR Unit, Royal Brompton Hospital, Sydney Street, London, UK.


A fifth of patients with primary degenerative mitral regurgitation continue to present with de novo ventricular dysfunction following surgery and higher rates of heart failure, morbidity, and mortality. This raises questions as to why the left ventricle (LV) might fail to recover and has led to support for better LV characterization; cardiac magnetic resonance (CMR) may play a role in this regard, pending further research and outcome data. CMR has widely acknowledged advantages, particularly in repeatability of measurements of volume and ejection fraction, yet recent guidelines relegate its use to cases where there is discordant information or poor-quality imaging from echocardiography because of the lack of data regarding the CMR-based ejection fraction threshold for surgery and CMR-based outcome data. This article reviews the current evidence regarding the role of CMR in an integrated surveillance and surgical timing programme.


Original languageEnglish
Pages (from-to)123-130
Number of pages8
JournalEuropean Heart Journal Cardiovascular Imaging
Issue number2
Early online date25 Oct 2018
Publication statusPublished - 1 Feb 2019


  • cardiac magnetic resonance, echocardiography, primary mitral regurgitation, ventricular remodelling