The effect of a small dose of chlorpromazine on a measure of 'cognitive inhibition'

Anthony Beech; TJ Powell; J McWilliam; Gordon Claridge

doi:10.1016/0191-8869(90)90026-N

The effect of a small dose of chlorpromazine on a measure of 'cognitive inhibition'

Anthony Beech, TJ Powell, J McWilliam, Gordon Claridge

Psychology

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

A double-blind drug/placebo experiment was conducted investigating the action of chlorpromazine on ‘cognitive inhibition’ in normal subjects. It has been suggested that such inhibition is reduced in schizophrenics and may be part of the mechanism that gives rise to positive symptomatology, because of a failure to screen out irrelevant material from consciousness. It was found that chlorpromazine (a drug routinely administered to schizophrenics) increased this inhibitory effectsin normal subjects.

Original language	English
Pages (from-to)	1141-1145
Journal	Personality and Individual Differences
Volume	11
Issue number	11
DOIs	https://doi.org/10.1016/0191-8869(90)90026-N
Publication status	Published - 1990

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title = "The effect of a small dose of chlorpromazine on a measure of 'cognitive inhibition'",

abstract = "A double-blind drug/placebo experiment was conducted investigating the action of chlorpromazine on {\textquoteleft}cognitive inhibition{\textquoteright} in normal subjects. It has been suggested that such inhibition is reduced in schizophrenics and may be part of the mechanism that gives rise to positive symptomatology, because of a failure to screen out irrelevant material from consciousness. It was found that chlorpromazine (a drug routinely administered to schizophrenics) increased this inhibitory effectsin normal subjects.",

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AU - Claridge, Gordon

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Y1 - 1990

N2 - A double-blind drug/placebo experiment was conducted investigating the action of chlorpromazine on ‘cognitive inhibition’ in normal subjects. It has been suggested that such inhibition is reduced in schizophrenics and may be part of the mechanism that gives rise to positive symptomatology, because of a failure to screen out irrelevant material from consciousness. It was found that chlorpromazine (a drug routinely administered to schizophrenics) increased this inhibitory effectsin normal subjects.

AB - A double-blind drug/placebo experiment was conducted investigating the action of chlorpromazine on ‘cognitive inhibition’ in normal subjects. It has been suggested that such inhibition is reduced in schizophrenics and may be part of the mechanism that gives rise to positive symptomatology, because of a failure to screen out irrelevant material from consciousness. It was found that chlorpromazine (a drug routinely administered to schizophrenics) increased this inhibitory effectsin normal subjects.

U2 - 10.1016/0191-8869(90)90026-N

DO - 10.1016/0191-8869(90)90026-N

M3 - Article

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VL - 11

SP - 1141

EP - 1145

JO - Personality and Individual Differences

JF - Personality and Individual Differences

IS - 11

ER -

The effect of a small dose of chlorpromazine on a measure of 'cognitive inhibition'

Abstract

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