The development of anti-cytokine agents for rheumatoid arthritis

Karim Raza; Jonathan Sherlock; Christopher Buckley

doi:10.1002/9780470571224.pse455

The development of anti-cytokine agents for rheumatoid arthritis

Karim Raza, Jonathan Sherlock, Christopher Buckley

Inflammation and Ageing

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

In this chapter, we will focus on cytokine-based therapeutics. Not only are developments in the identification and targeting of cytokines vital, but the detailed pharmacology of the therapeutics themselves is of critical importance. The proof of concept demonstrated by the success of anti- tumor necrosis factor (TNF) agents, combined with the experimental ease with which cytokines can be investigated and manipulated, has opened the future of rheumatology to exciting new conceptual and therapeutic prospects.

Original language	English
Title of host publication	Development of Therapeutic Agents Handbook
Publisher	Wiley
Pages	881-986
DOIs	https://doi.org/10.1002/9780470571224.pse455
Publication status	Published - 2012

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abstract = "In this chapter, we will focus on cytokine-based therapeutics. Not only are developments in the identification and targeting of cytokines vital, but the detailed pharmacology of the therapeutics themselves is of critical importance. The proof of concept demonstrated by the success of anti- tumor necrosis factor (TNF) agents, combined with the experimental ease with which cytokines can be investigated and manipulated, has opened the future of rheumatology to exciting new conceptual and therapeutic prospects.",

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The development of anti-cytokine agents for rheumatoid arthritis

Abstract

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