Research output: Contribution to journalArticlepeer-review


  • Stephen Ph Alexander
  • Eamonn Kelly
  • Neil V Marrion
  • John A Peters
  • Elena Faccenda
  • And 12 others
  • Simon D Harding
  • Adam J Pawson
  • Joanna L Sharman
  • Christopher Southan
  • O Peter Buneman
  • John A Cidlowski
  • Arthur Christopoulos
  • Anthony P Davenport
  • Doriano Fabbro
  • Michael Spedding
  • Jörg Striessnig
  • Jamie A Davies

Colleges, School and Institutes

External organisations

  • Department of Oncology, Cancer Research UK and MRC Oxford Institute for Radiation Oncology, University of Oxford, Oxford OX3 7LE, UK; School of Life Sciences, The Medical School, University of Nottingham, Nottingham NG7 2UH, UK.
  • University of Bristol
  • University of Dundee
  • University of Edinburgh, The
  • Laboratory for Foundations of Computer Science, School of Informatics; University of Edinburgh; Edinburgh EH8 9LE United Kingdom
  • National Institutes of Health
  • Monash University
  • University of Cambridge
  • PIQUR Therapeutics; Basel 4057 Switzerland
  • Spedding Research Solutions SARL; Le Vésinet 78110 France
  • Pharmacology and Toxicology; Institute of Pharmacy; University of Innsbruck A-6020 Innsbruck Austria


The Concise Guide to PHARMACOLOGY 2017/18 is the third in this series of biennial publications. This version provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access knowledgebase of drug targets and their ligands (, which provides more detailed views of target and ligand properties. Although the Concise Guide represents approximately 400 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point‐in‐time record that will survive database updates. The full contents of this section can be found at In addition to this overview, in which are identified ‘Other protein targets’ which fall outside of the subsequent categorisation, there are eight areas of focus: G protein‐coupled receptors, ligand‐gated ion channels, voltage‐gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid‐2017, and supersedes data presented in the 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature Committee of the Union of Basic and Clinical Pharmacology (NC‐IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.


Original languageEnglish
Pages (from-to)S1-S16
JournalBritish Journal of Pharmacology
Early online date21 Oct 2017
Publication statusPublished - 1 Dec 2017