The aetiology of idiopathic Parkinson's disease

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Colleges, School and Institutes

Abstract

Agents potentially involved in the aetiology of idiopathic Parkinson's disease are discussed. These include factors regulating dopaminergic neurogenesis (Nurr 1, Ptx-3, and Lmx1b) and related proteins, together with genes involved in familial Parkinson's disease (alpha synuclein, parkin, and ubiquitin carboxy terminal hydroxylase L1), and endogenous and environmental agents.

Details

Original languageEnglish
Pages (from-to)369-380
Number of pages12
JournalMolecular Pathology
Volume54
Issue number6
Publication statusPublished - 1 Dec 2001

Keywords

  • parkin, Parkinson's disease, alpha synuclein, ubiquitin carboxy terminal hydroxylase L1, transcription factors, environmental agents