Systems biologists seek fuller integration of systems biology approaches in new cancer research programs

Research output: Contribution to journalArticle

Authors

  • Olaf Wolkenhauer
  • Charles Auffray
  • Simone Baltrusch
  • Nils Blüthgen
  • Helen Byrne
  • Marta Cascante
  • Andrea Ciliberto
  • Trevor Dale
  • Dirk Drasdo
  • David Fell
  • James E Ferrell
  • Daniel Gallahan
  • Robert Gatenby
  • Brian D Harms
  • Hanspeter Herzel
  • Christian Junghanss
  • Manfred Kunz
  • Ingeborg van Leeuwen
  • Philippe Lenormand
  • Francis Levi
  • Michael Linnebacher
  • John Lowengrub
  • Philip K Maini
  • Arif Malik
  • Katja Rateitschak
  • Owen Sansom
  • Reinhold Schäfer
  • Karsten Schürrle
  • Christine Sers
  • Santiago Schnell
  • Darryl Shibata
  • John Tyson
  • Julio Vera
  • Michael White
  • Boris Zhivotovsky
  • Robert Jaster

Colleges, School and Institutes

External organisations

  • University of Rostock
  • CNRS, Villejuif, France
  • Charité, Berlin, Germany
  • University of Nottingham
  • University of Barcelona
  • IFOM IEO Campus Oncogenom
  • Cardiff Univ
  • INRIA, Le Chesnay, France
  • Oxford Brookes Univ
  • Stanford Univ
  • National Cancer Institute, Bethesda, Maryland
  • University of Liverpool

Abstract

Systems biology takes an interdisciplinary approach to the systematic study of complex interactions in biological systems. This approach seeks to decipher the emergent behaviors of complex systems rather than focusing only on their constituent properties. As an increasing number of examples illustrate the value of systems biology approaches to understand the initiation, progression, and treatment of cancer, systems biologists from across Europe and the United States hope for changes in the way their field is currently perceived among cancer researchers. In a recent EU-US workshop, supported by the European Commission, the German Federal Ministry for Education and Research, and the National Cancer Institute of the NIH, the participants discussed the strengths, weaknesses, hurdles, and opportunities in cancer systems biology.

Details

Original languageEnglish
Pages (from-to)12-3
Number of pages2
JournalCancer Research
Volume70
Issue number1
Publication statusPublished - 2010