Synthesis of an Achiral Isomer of Lipoic Acid As an Anchor Group for SAM Formation on Gold Surfaces

Research output: Contribution to journalArticle


  • KM Joly
  • Giorgio Mirri
  • Y Willener
  • Sarah Horswell
  • CJ Moody

Colleges, School and Institutes


Isolipoic acid, a symmetrical and achiral isomer of the commonly-used alpha-lipoic acid, has previously been overlooked as a tether group for the formation of self-assembled monolayers (SAMs). Here its ready synthesis through a new route and its functionalization with ferrocenyl groups for redox-active SAM formation on gold electrodes are described.


Original languageEnglish
Pages (from-to)2395-2398
Number of pages4
JournalThe Journal of Organic Chemistry
Issue number7
Publication statusPublished - 1 Apr 2010