Summary from an international cancer seminar focused on human papillomavirus (HPV)-positive oropharynx cancer, convened by scientists at IARC and NCI

Research output: Contribution to journalArticle

Authors

  • Aimée R Kreimer
  • Anil K Chaturvedi
  • Laia Alemany
  • Devasena Anantharaman
  • Freddie Bray
  • Mary Carrington
  • John Doorbar
  • Gypsyamber D'Souza
  • Carole Fakhry
  • Robert L Ferris
  • Maura Gillison
  • D Neil Hayes
  • Allan Hildesheim
  • Shao Hui Huang
  • Luiz P Kowalski
  • Krystle A Lang Kuhs
  • James Lewis
  • Douglas R Lowy
  • Andy Ness
  • Michael Pawlita
  • Maisa Pinheiro
  • John Schiller
  • Meredith S Shiels
  • Joseph Tota
  • Lisa Mirabello
  • Saman Warnakulasuriya
  • Tim Waterboer
  • William Westra
  • Stephen Chanock
  • Paul Brennan

Colleges, School and Institutes

External organisations

  • National Cancer Research Institute
  • Catalan Institute of Oncology (ICO)
  • Rajiv Gandhi Centre for Biotechnology
  • International Agency for Research on Cancer
  • Ragon Institute of MGH
  • Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge Department of Oncology, University of Cambridge, Addenbrooke's Hospital, Cambridge Cambridge Experimental Cancer Medicine Centre and NIHR Cambridge Biomedical Research Centre, Cambridge, UK.
  • Bloomberg School of Public Health, Johns Hopkins University
  • UPMC Hillman Cancer Center
  • The University of Texas MD Anderson Cancer Center
  • The University of Tennessee Health Science Center
  • Toronto Centre for Liver Disease, University of Toronto, Toronto General Hospital, Toronto, Ontario, Canada.
  • A.C. Camargo Cancer Center
  • Vanderbilt University Medical Center
  • Institute for Head and Neck Studies and Education (InHANSE)
  • Bristol Haematology And Oncology Centre, University Hospital Bristol NHS Foundation Trust, Bristol, UK.
  • Division of Molecular Genetics, Heidelberg Center for Personalized Oncology, German Cancer Research Consortium, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • King's Health Partners Cancer Biobank, King's College London, London, UK.
  • Icahn School of Medicine at Mount Sinai

Abstract

Cancer of the oropharynx has attracted considerable attention in recent years given: (1) an increasing incidence in selected populations over the past three decades; (2) the discovery of human papillomavirus (HPV) infection as the driver of the increase, as opposed to the traditional risk factors such as tobacco (smoking and chewing) and alcohol; and (3) the promise of new prevention and treatment strategies. As a result of such developments, the International Agency for Research on Cancer (IARC) and the US National Cancer Institute (NCI), convened the fourth Cancer Seminar meeting in November 2018 to focus on this topic. This report summarizes the proceedings: a review of recent science on the descriptive epidemiology, etiology, biology, genetics, early detection, pathology and treatment of HPV-positive oropharyngeal cancer, and the formulation of key research questions to be addressed.

Bibliographic note

Published by Elsevier Ltd.

Details

Original languageEnglish
Pages (from-to)104736
JournalOral Oncology
Volume108
Publication statusPublished - 5 Sep 2020