TY - JOUR
T1 - Statin therapy in South-Asian patients: clinical implications beyond lipid lowering?
AU - Jaumdally, JR
AU - Varma, Chetan
AU - Lip, Gregory
PY - 2007/6/1
Y1 - 2007/6/1
N2 - Whether used as primary or secondary prevention, 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) can lead to a significant reduction in mortality and morbidity from cardiovascular disease. Given the benefit in halting atherosclerotic disease progression in patients with stable and acute coronary syndrome, the potential for use in South-Asians remains largely unreported. As this ethnic group has a high rate of coronary events at a younger age, with more extensive and diffuse atheroma, the authors review the impact of statins in relation to observed lipid profiles, as well as novel markers of vascular disease.
AB - Whether used as primary or secondary prevention, 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) can lead to a significant reduction in mortality and morbidity from cardiovascular disease. Given the benefit in halting atherosclerotic disease progression in patients with stable and acute coronary syndrome, the potential for use in South-Asians remains largely unreported. As this ethnic group has a high rate of coronary events at a younger age, with more extensive and diffuse atheroma, the authors review the impact of statins in relation to observed lipid profiles, as well as novel markers of vascular disease.
U2 - 10.1517/14656566.8.9.1235
DO - 10.1517/14656566.8.9.1235
M3 - Article
C2 - 17563259
SN - 1941-7225
VL - 8
SP - 1235
EP - 1243
JO - American Journal of Hypertension
JF - American Journal of Hypertension
IS - 9
ER -