TY - JOUR
T1 - Spontaneous baroreflex sensitivity in young and older people during voluntary and electrically evoked isometric exercise
AU - Carrington, Charlotte
AU - White, Michael
PY - 2002/9/1
Y1 - 2002/9/1
N2 - BACKGROUND: In young people, cardiovagal baroreflex sensitivity alters during isometric exercise. We investigated whether the reduced resting baroreflex sensitivity seen with increasing age is similarly altered during exercise. METHODS: Cardiovagal baroreflex sensitivity was examined in 8 young (age+/-SEM, 25+/-1.7 years) and 9 older (61+/-3.0 years) subjects, using sequence analysis during voluntary and electrically evoked isometric exercise (at 30% maximum voluntary strength) and during subsequent post-exercise circulatory occlusion. RESULTS: In all phases of both conditions, baroreflex sensitivity was significantly reduced in the older group compared with the young group. (Median (interquartile range), voluntary 7.0 (4.4) vs 3.6 (3.8) ms x mmHg(-1), post-exercise circulatory occlusion 9.0 (8.2) vs 4.6 (4.0) ms x mmHg(-1); electrically evoked 6.6 (10.6) vs 3.2 (3.6) ms x mmHg(-1), post-exercise circulatory occlusion 8.3 (7.7) vs 2.9 (2.2) ms x mmHg(-1), young vs older respectively; P
AB - BACKGROUND: In young people, cardiovagal baroreflex sensitivity alters during isometric exercise. We investigated whether the reduced resting baroreflex sensitivity seen with increasing age is similarly altered during exercise. METHODS: Cardiovagal baroreflex sensitivity was examined in 8 young (age+/-SEM, 25+/-1.7 years) and 9 older (61+/-3.0 years) subjects, using sequence analysis during voluntary and electrically evoked isometric exercise (at 30% maximum voluntary strength) and during subsequent post-exercise circulatory occlusion. RESULTS: In all phases of both conditions, baroreflex sensitivity was significantly reduced in the older group compared with the young group. (Median (interquartile range), voluntary 7.0 (4.4) vs 3.6 (3.8) ms x mmHg(-1), post-exercise circulatory occlusion 9.0 (8.2) vs 4.6 (4.0) ms x mmHg(-1); electrically evoked 6.6 (10.6) vs 3.2 (3.6) ms x mmHg(-1), post-exercise circulatory occlusion 8.3 (7.7) vs 2.9 (2.2) ms x mmHg(-1), young vs older respectively; P
KW - autonomic nervous function
KW - heart rate
KW - blood pressure
KW - cardiovagal baroreflex
UR - http://www.scopus.com/inward/record.url?scp=0036750607&partnerID=8YFLogxK
U2 - 10.1093/ageing/31.5.359
DO - 10.1093/ageing/31.5.359
M3 - Article
C2 - 12242198
VL - 31
SP - 359
EP - 364
JO - Age and Ageing
JF - Age and Ageing
IS - 5
ER -