Solving the WAVE function

Robert Insall, Simone Blagg

Research output: Contribution to journalReview article

26 Citations (Scopus)

Abstract

SCAR/WAVE proteins are central regulators of cell motility that coordinate actin reorganization through activation of the Arp2/3 complex. Their activity is controlled by a large complex with four other members. A new study contradicts earlier work by suggesting that the entire complex is required for SCAR/WAVE activity at the leading edge.
Original languageEnglish
Pages (from-to)279-281
Number of pages3
JournalNature Cell Biology
Volume6
DOIs
Publication statusPublished - 1 Jan 2004

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