Solving the WAVE function

Research output: Contribution to journalReview article


Colleges, School and Institutes


SCAR/WAVE proteins are central regulators of cell motility that coordinate actin reorganization through activation of the Arp2/3 complex. Their activity is controlled by a large complex with four other members. A new study contradicts earlier work by suggesting that the entire complex is required for SCAR/WAVE activity at the leading edge.


Original languageEnglish
Pages (from-to)279-281
Number of pages3
JournalNature Cell Biology
Publication statusPublished - 1 Jan 2004