@inproceedings{8740e533932448a893b670aad7ca8466,
title = "Sol-gel preparation of HAp-coated silica macrospheres from water glass and their protein adsorption",
abstract = "Silica gel macrospheres of 2~4 mm in size, and wrapped with Ca-alginate chelate film were prepared as the substrate for hydroxyapatite coating layer, using water glass as the silica source. Those Ca-SiO2 macrospheres were soaked in a 1:1 (volume) mixture of ethanol and 0.1 M Na 2HPO4 to deposit hydroxyapatite layer (HAp-SiO2 macrospheres). Adsorption of bovine serum albumin and egg lysozyme on those Ca-SiO2 and HAp-SiO2 macrospheres under physiological pH (7.2) was well correlated to the Langmuir-type adsorption equation. The electrostatic interactions between the protein molecules and those macrospheres well interpret the adsorption isotherms, while the mesopores in the Ca-SiO 2contributed to some extent. A multi-layer adsorption model was proposed.",
keywords = "Hydroxyapatite coating, Protein adsorption, Silica gel macrosphere, Water glass",
author = "Jie Li and Yuki Shirosaki and Satoshi Hayakawa and Artemis Stamboulis and Akiyoshi Osaka",
year = "2013",
doi = "10.4028/www.scientific.net/KEM.529-530.637",
language = "English",
isbn = "9783037855171",
series = "Key Engineering Materials",
publisher = "Trans Tech Publications Ltd",
number = "1",
pages = "637--640",
booktitle = "Bioceramics 24",
edition = "1",
note = "24th Symposium and Annual Meeting of International Society for Ceramics in Medicine, ISCM 2012 ; Conference date: 21-10-2012 Through 24-10-2012",
}