Social environmental risk factors for transition to psychosis in an Ultra-High Risk population

Brian O'Donoghue; Barnaby Nelson; Hok Pan Yuen; Abbie Lane; Stephen Wood; Andrew Thompson; Ashleigh Lin; Patrick McGorry; Alison R Yung

doi:10.1016/j.schres.2014.10.050

Social environmental risk factors for transition to psychosis in an Ultra-High Risk population

Brian O'Donoghue, Barnaby Nelson, Hok Pan Yuen, Abbie Lane, Stephen Wood, Andrew Thompson, Ashleigh Lin, Patrick McGorry, Alison R Yung

Psychology

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

264 Downloads (Pure)

Abstract

OBJECTIVE: Despite social environmental factors such as deprivation, urbanicity, migration and adversity being established risk factors for psychotic disorders, there is a paucity of knowledge on the influence of social environmental risk factors in the UHR population. Firstly, we aimed to investigate the association between social deprivation and risk of transition and secondly, we aimed to investigate the association between migration status and the risk of transition.

METHOD: UHR individuals at the Personal Assessment and Crisis Evaluation (PACE) service in Melbourne were included. Social deprivation as assessed according to postal code area of residence was obtained from census data and Cox regression analysis was used to calculate hazard ratios.

RESULTS: A total of 219 UHR individuals were included and over the median follow-up time of 4.8years, 32 individuals (14.6%) were known to have transitioned to a psychotic disorder. 8.8% of UHR individuals were first generation migrants and 41.9% were second generation migrants. The level of social deprivation was not associated with the risk of transition (p=0.83). Similarly, first or second generation migrants did not have an increased risk of transition to psychosis (p=0.84).

CONCLUSIONS: Despite being established risk factors for psychotic disorders, social deprivation and migrant status have not been found to increase the risk of transition in a UHR population.

Original language	English
Pages (from-to)	150-5
Number of pages	6
Journal	Schizophrenia Research
Volume	161
Issue number	2-3
Early online date	28 Nov 2014
DOIs	https://doi.org/10.1016/j.schres.2014.10.050
Publication status	Published - Feb 2015

Bibliographical note

Keywords

Psychosis
Social deprivation
Migrants
Ultra-High Risk for psychosis

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Wood_Social_environmental_risk_factors_Schizophrenia_Research_2014Accepted author manuscript, 94.7 KBLicence: None: All rights reserved

Cite this

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title = "Social environmental risk factors for transition to psychosis in an Ultra-High Risk population",

abstract = "OBJECTIVE: Despite social environmental factors such as deprivation, urbanicity, migration and adversity being established risk factors for psychotic disorders, there is a paucity of knowledge on the influence of social environmental risk factors in the UHR population. Firstly, we aimed to investigate the association between social deprivation and risk of transition and secondly, we aimed to investigate the association between migration status and the risk of transition.METHOD: UHR individuals at the Personal Assessment and Crisis Evaluation (PACE) service in Melbourne were included. Social deprivation as assessed according to postal code area of residence was obtained from census data and Cox regression analysis was used to calculate hazard ratios.RESULTS: A total of 219 UHR individuals were included and over the median follow-up time of 4.8years, 32 individuals (14.6%) were known to have transitioned to a psychotic disorder. 8.8% of UHR individuals were first generation migrants and 41.9% were second generation migrants. The level of social deprivation was not associated with the risk of transition (p=0.83). Similarly, first or second generation migrants did not have an increased risk of transition to psychosis (p=0.84).CONCLUSIONS: Despite being established risk factors for psychotic disorders, social deprivation and migrant status have not been found to increase the risk of transition in a UHR population.",

keywords = "Psychosis, Social deprivation, Migrants, Ultra-High Risk for psychosis",

author = "Brian O'Donoghue and Barnaby Nelson and Yuen, {Hok Pan} and Abbie Lane and Stephen Wood and Andrew Thompson and Ashleigh Lin and Patrick McGorry and Yung, {Alison R}",

year = "2015",

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doi = "10.1016/j.schres.2014.10.050",

language = "English",

volume = "161",

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journal = "Schizophrenia Research",

issn = "0920-9964",

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T1 - Social environmental risk factors for transition to psychosis in an Ultra-High Risk population

AU - O'Donoghue, Brian

AU - Nelson, Barnaby

AU - Yuen, Hok Pan

AU - Lane, Abbie

AU - Wood, Stephen

AU - Thompson, Andrew

AU - Lin, Ashleigh

AU - McGorry, Patrick

AU - Yung, Alison R

PY - 2015/2

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N2 - OBJECTIVE: Despite social environmental factors such as deprivation, urbanicity, migration and adversity being established risk factors for psychotic disorders, there is a paucity of knowledge on the influence of social environmental risk factors in the UHR population. Firstly, we aimed to investigate the association between social deprivation and risk of transition and secondly, we aimed to investigate the association between migration status and the risk of transition.METHOD: UHR individuals at the Personal Assessment and Crisis Evaluation (PACE) service in Melbourne were included. Social deprivation as assessed according to postal code area of residence was obtained from census data and Cox regression analysis was used to calculate hazard ratios.RESULTS: A total of 219 UHR individuals were included and over the median follow-up time of 4.8years, 32 individuals (14.6%) were known to have transitioned to a psychotic disorder. 8.8% of UHR individuals were first generation migrants and 41.9% were second generation migrants. The level of social deprivation was not associated with the risk of transition (p=0.83). Similarly, first or second generation migrants did not have an increased risk of transition to psychosis (p=0.84).CONCLUSIONS: Despite being established risk factors for psychotic disorders, social deprivation and migrant status have not been found to increase the risk of transition in a UHR population.

AB - OBJECTIVE: Despite social environmental factors such as deprivation, urbanicity, migration and adversity being established risk factors for psychotic disorders, there is a paucity of knowledge on the influence of social environmental risk factors in the UHR population. Firstly, we aimed to investigate the association between social deprivation and risk of transition and secondly, we aimed to investigate the association between migration status and the risk of transition.METHOD: UHR individuals at the Personal Assessment and Crisis Evaluation (PACE) service in Melbourne were included. Social deprivation as assessed according to postal code area of residence was obtained from census data and Cox regression analysis was used to calculate hazard ratios.RESULTS: A total of 219 UHR individuals were included and over the median follow-up time of 4.8years, 32 individuals (14.6%) were known to have transitioned to a psychotic disorder. 8.8% of UHR individuals were first generation migrants and 41.9% were second generation migrants. The level of social deprivation was not associated with the risk of transition (p=0.83). Similarly, first or second generation migrants did not have an increased risk of transition to psychosis (p=0.84).CONCLUSIONS: Despite being established risk factors for psychotic disorders, social deprivation and migrant status have not been found to increase the risk of transition in a UHR population.

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KW - Migrants

KW - Ultra-High Risk for psychosis

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JO - Schizophrenia Research

JF - Schizophrenia Research

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Social environmental risk factors for transition to psychosis in an Ultra-High Risk population

Abstract

Bibliographical note

Keywords

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