Size and shape affects the antimicrobial activity of quaternized nanoparticles

Maria Inam; Jeffrey C. Foster; Jingyi Gao; Yuanxiu Hong; Jianzhong Du; Andrew P. Dove; Rachel K. O'Reilly

doi:10.1002/pola.29195

Size and shape affects the antimicrobial activity of quaternized nanoparticles

Maria Inam, Jeffrey C. Foster, Jingyi Gao, Yuanxiu Hong, Jianzhong Du, Andrew P. Dove, Rachel K. O'Reilly

Chemistry

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

127 Downloads (Pure)

Abstract

Crystallization driven self‐assembly (CDSA) was utilized to prepare quaternized nanoparticles with spherical or platelet morphologies of different sizes to explore the effect of size and shape on their antibacterial activity. Small 2D platelets (< 1 µm) exhibited greater antibacterial activity than larger 2D platelets (ca. 4 µm), their corresponding spherical constructs, and unassembled polymer chains. This activity was dependent on the size, shape, and cell membrane structure of the bacteria.

Original language	English
Number of pages	5
Journal	Journal of Polymer Science. Part A: Polymer Chemistry
Early online date	18 Oct 2018
DOIs	https://doi.org/10.1002/pola.29195
Publication status	E-pub ahead of print - 18 Oct 2018

Keywords

biological activity
platelets
polymers
self-assembly
size effects

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Maria_Inam_et_al_Size_and_shape_affects_the_antimicrobial_activity_of_quaternized_nanoparticles_Journal_of_Polymer_Science_Part_A_Polymer_Chemistry_2018
Checked for eligibility: 13/11/2018 This is the peer reviewed version of the following article: Inam, M. , Foster, J. C., Gao, J. , Hong, Y. , Du, J. , Dove, A. P. and O'Reilly, R. K. (2018), Size and shape affects the antimicrobial activity of quaternized nanoparticles. J. Polym. Sci. Part A: Polym. Chem.. . doi:10.1002/pola.29195, which has been published in final form at https://doi.org/10.1002/pola.29195. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
Accepted author manuscript, 1.03 MBLicence: Other (please specify with Rights Statement)

Cite this

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AU - Du, Jianzhong

AU - Dove, Andrew P.

AU - O'Reilly, Rachel K.

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Size and shape affects the antimicrobial activity of quaternized nanoparticles

Abstract

Keywords

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