Abstract
Background-Cardiac resynchronization therapy produces both short-term hemodynamic and long-term symptomatic/mortality benefits in symptomatic heart failure patients with a QRS duration > 120 ms. This is conventionally believed to be due principally to relief of dyssynchrony, although we recently showed that relief of external constraint to left ventricular filling may also play a role. In this study, we evaluated the short-term hemodynamic effects in symptomatic patients with a QRS duration <120 ms and no evidence of dyssynchrony on conventional criteria and assessed the effects on contractility and external constraint.
Methods and Results-Thirty heart failure patients (New York Heart Association class III/IV) with a left ventricular ejection fraction
Original language | English |
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Pages (from-to) | 1687-1694 |
Number of pages | 8 |
Journal | Circulation |
Volume | 120 |
Issue number | 17 |
DOIs | |
Publication status | Published - 1 Oct 2009 |
Keywords
- heart failure
- hemodynamics
- pacing
- cardiac output