Shining a Light on Awareness: A Review of Functional Near-Infrared Spectroscopy for Prolonged Disorders of Consciousness

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@article{e5b723aeca2549f0b3989de6e875aadf,
title = "Shining a Light on Awareness:: A Review of Functional Near-Infrared Spectroscopy for Prolonged Disorders of Consciousness",
abstract = "Qualitative clinical assessments of the recovery of awareness after severe brain injury require an assessor to differentiate purposeful behaviour from spontaneous behaviour. As many such behaviours are minimal and inconsistent, behavioural assessments are susceptible to diagnostic errors. Advanced neuroimaging tools can bypass behavioural responsiveness and reveal evidence of covert awareness and cognition within the brains of some patients, thus providing a means for more accurate diagnoses, more accurate prognoses, and, in some instances, facilitated communication. The majority of reports to date have employed the neuroimaging methods of functional magnetic resonance imaging, positron emission tomography, and electroencephalography (EEG). However, each neuroimaging method has its own advantages and disadvantages (e.g. signal resolution, accessibility, etc.). Here, we describe a burgeoning technique of non-invasive optical neuroimaging – functional near-infrared spectroscopy (fNIRS) – and review its potential to address the clinical challenges of prolonged disorders of consciousness. We also outline the potential for simultaneously-acquired EEG to complement the fNIRS signal, and suggest the future directions of research that are required in order to realise its clinical potential.",
keywords = "disorders of consciousness , functional near-infrared spectroscopy , electroencephalography , motor imagery , data fusion , brain-computer interface",
author = "Mohammed Rupawala and Hamid Dehghani and Lucas, {Samuel J. E.} and Peter Tino and Damian Cruse",
year = "2018",
month = "5",
day = "22",
doi = "10.3389/fneur.2018.00350",
language = "English",
volume = "9",
journal = "Frontiers in neurology",
issn = "1664-2295",
publisher = "Frontiers",

}

RIS

TY - JOUR

T1 - Shining a Light on Awareness:

T2 - A Review of Functional Near-Infrared Spectroscopy for Prolonged Disorders of Consciousness

AU - Rupawala, Mohammed

AU - Dehghani, Hamid

AU - Lucas, Samuel J. E.

AU - Tino, Peter

AU - Cruse, Damian

PY - 2018/5/22

Y1 - 2018/5/22

N2 - Qualitative clinical assessments of the recovery of awareness after severe brain injury require an assessor to differentiate purposeful behaviour from spontaneous behaviour. As many such behaviours are minimal and inconsistent, behavioural assessments are susceptible to diagnostic errors. Advanced neuroimaging tools can bypass behavioural responsiveness and reveal evidence of covert awareness and cognition within the brains of some patients, thus providing a means for more accurate diagnoses, more accurate prognoses, and, in some instances, facilitated communication. The majority of reports to date have employed the neuroimaging methods of functional magnetic resonance imaging, positron emission tomography, and electroencephalography (EEG). However, each neuroimaging method has its own advantages and disadvantages (e.g. signal resolution, accessibility, etc.). Here, we describe a burgeoning technique of non-invasive optical neuroimaging – functional near-infrared spectroscopy (fNIRS) – and review its potential to address the clinical challenges of prolonged disorders of consciousness. We also outline the potential for simultaneously-acquired EEG to complement the fNIRS signal, and suggest the future directions of research that are required in order to realise its clinical potential.

AB - Qualitative clinical assessments of the recovery of awareness after severe brain injury require an assessor to differentiate purposeful behaviour from spontaneous behaviour. As many such behaviours are minimal and inconsistent, behavioural assessments are susceptible to diagnostic errors. Advanced neuroimaging tools can bypass behavioural responsiveness and reveal evidence of covert awareness and cognition within the brains of some patients, thus providing a means for more accurate diagnoses, more accurate prognoses, and, in some instances, facilitated communication. The majority of reports to date have employed the neuroimaging methods of functional magnetic resonance imaging, positron emission tomography, and electroencephalography (EEG). However, each neuroimaging method has its own advantages and disadvantages (e.g. signal resolution, accessibility, etc.). Here, we describe a burgeoning technique of non-invasive optical neuroimaging – functional near-infrared spectroscopy (fNIRS) – and review its potential to address the clinical challenges of prolonged disorders of consciousness. We also outline the potential for simultaneously-acquired EEG to complement the fNIRS signal, and suggest the future directions of research that are required in order to realise its clinical potential.

KW - disorders of consciousness

KW - functional near-infrared spectroscopy

KW - electroencephalography

KW - motor imagery

KW - data fusion

KW - brain-computer interface

U2 - 10.3389/fneur.2018.00350

DO - 10.3389/fneur.2018.00350

M3 - Article

VL - 9

JO - Frontiers in neurology

JF - Frontiers in neurology

SN - 1664-2295

M1 - 350

ER -