TY - JOUR
T1 - Shifting the limits in wheat research and breeding using a fully annotated reference genome
AU - International Wheat Genome Sequencing Consortium (IWGSC)
AU - Appels, Rudi
AU - Eversole, Kellye
AU - Feuillet, Catherine
AU - Keller, Beat
AU - Rogers, Jane
AU - Stein, Nils
AU - Pozniak, Curtis J
AU - Stein, Nils
AU - Choulet, Frédéric
AU - Distelfeld, Assaf
AU - Eversole, Kellye
AU - Poland, Jesse
AU - Rogers, Jane
AU - Ronen, Gil
AU - Sharpe, Andrew G
AU - Pozniak, Curtis
AU - Ronen, Gil
AU - Stein, Nils
AU - Barad, Omer
AU - Baruch, Kobi
AU - Choulet, Frédéric
AU - Keeble-Gagnère, Gabriel
AU - Mascher, Martin
AU - Sharpe, Andrew G
AU - Ben-Zvi, Gil
AU - Josselin, Ambre-Aurore
AU - Stein, Nils
AU - Mascher, Martin
AU - Himmelbach, Axel
AU - Choulet, Frédéric
AU - Keeble-Gagnère, Gabriel
AU - Mascher, Martin
AU - Rogers, Jane
AU - Balfourier, François
AU - Gutierrez-Gonzalez, Juan
AU - Hayden, Matthew
AU - Josselin, Ambre-Aurore
AU - Koh, ChuShin
AU - Muehlbauer, Gary
AU - Pasam, Raj K
AU - Paux, Etienne
AU - Pozniak, Curtis J
AU - Rigault, Philippe
AU - Sharpe, Andrew G
AU - Tibbits, Josquin
AU - Tiwari, Vijay
AU - Choulet, Frédéric
AU - Keeble-Gagnère, Gabriel
AU - Mascher, Martin
AU - Josselin, Ambre-Aurore
AU - Borrill, Philippa
N1 - Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.
PY - 2018/8/17
Y1 - 2018/8/17
N2 - An annotated reference sequence representing the hexaploid bread wheat genome in 21 pseudomolecules has been analyzed to identify the distribution and genomic context of coding and noncoding elements across the A, B, and D subgenomes. With an estimated coverage of 94% of the genome and containing 107,891 high-confidence gene models, this assembly enabled the discovery of tissue- and developmental stage-related coexpression networks by providing a transcriptome atlas representing major stages of wheat development. Dynamics of complex gene families involved in environmental adaptation and end-use quality were revealed at subgenome resolution and contextualized to known agronomic single-gene or quantitative trait loci. This community resource establishes the foundation for accelerating wheat research and application through improved understanding of wheat biology and genomics-assisted breeding.
AB - An annotated reference sequence representing the hexaploid bread wheat genome in 21 pseudomolecules has been analyzed to identify the distribution and genomic context of coding and noncoding elements across the A, B, and D subgenomes. With an estimated coverage of 94% of the genome and containing 107,891 high-confidence gene models, this assembly enabled the discovery of tissue- and developmental stage-related coexpression networks by providing a transcriptome atlas representing major stages of wheat development. Dynamics of complex gene families involved in environmental adaptation and end-use quality were revealed at subgenome resolution and contextualized to known agronomic single-gene or quantitative trait loci. This community resource establishes the foundation for accelerating wheat research and application through improved understanding of wheat biology and genomics-assisted breeding.
KW - Atlases as Topic
KW - Bread
KW - Breeding
KW - Gene Expression Regulation, Developmental
KW - Gene Expression Regulation, Plant
KW - Genome, Plant
KW - Molecular Sequence Annotation
KW - Multigene Family
KW - Phylogeny
KW - Quantitative Trait Loci
KW - Reference Standards
KW - Transcriptome
KW - Triticum/anatomy & histology
U2 - 10.1126/science.aar7191
DO - 10.1126/science.aar7191
M3 - Article
C2 - 30115783
SN - 0036-8075
VL - 361
JO - Science
JF - Science
IS - 6403
M1 - eaar7191
ER -