Sex differences in the interleukin-6 response to acute psychological stress

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@article{0792ca9d6efa40b4812a9c8c528a51e2,
title = "Sex differences in the interleukin-6 response to acute psychological stress",
abstract = "Interleukin-6 (IL-6), an immune regulator that helps coordinate the inflammatory response, may mediate inflammatory disease exacerbation associated with stress. Twenty men and twenty women completed a single session, comprising baseline (20 min), mental arithmetic task (8 min), and recovery (60 min). Blood samples, taken at baseline, immediately after the task, and at +30 and +60 min recovery were analysed for plasma IL-6. Overall, IL-6 increased linearly from baseline to +60 min recovery, and a sex difference was found in the IL-6 response, with men peaking earlier than women. These findings confirm a small delayed IL-6 increase after acute laboratory stress, and reveal sex differences in the profile of the IL-6 response.",
keywords = "sex differences, interleukin-6, acute stress",
author = "Kathryn Edwards and Victoria Burns and Christopher Ring and Douglas Carroll",
year = "2006",
month = mar,
day = "1",
doi = "10.1016/j.biopsycho.2005.06.006",
language = "English",
volume = "71",
pages = "236--239",
journal = "Biological Psychology",
issn = "0301-0511",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Sex differences in the interleukin-6 response to acute psychological stress

AU - Edwards, Kathryn

AU - Burns, Victoria

AU - Ring, Christopher

AU - Carroll, Douglas

PY - 2006/3/1

Y1 - 2006/3/1

N2 - Interleukin-6 (IL-6), an immune regulator that helps coordinate the inflammatory response, may mediate inflammatory disease exacerbation associated with stress. Twenty men and twenty women completed a single session, comprising baseline (20 min), mental arithmetic task (8 min), and recovery (60 min). Blood samples, taken at baseline, immediately after the task, and at +30 and +60 min recovery were analysed for plasma IL-6. Overall, IL-6 increased linearly from baseline to +60 min recovery, and a sex difference was found in the IL-6 response, with men peaking earlier than women. These findings confirm a small delayed IL-6 increase after acute laboratory stress, and reveal sex differences in the profile of the IL-6 response.

AB - Interleukin-6 (IL-6), an immune regulator that helps coordinate the inflammatory response, may mediate inflammatory disease exacerbation associated with stress. Twenty men and twenty women completed a single session, comprising baseline (20 min), mental arithmetic task (8 min), and recovery (60 min). Blood samples, taken at baseline, immediately after the task, and at +30 and +60 min recovery were analysed for plasma IL-6. Overall, IL-6 increased linearly from baseline to +60 min recovery, and a sex difference was found in the IL-6 response, with men peaking earlier than women. These findings confirm a small delayed IL-6 increase after acute laboratory stress, and reveal sex differences in the profile of the IL-6 response.

KW - sex differences

KW - interleukin-6

KW - acute stress

U2 - 10.1016/j.biopsycho.2005.06.006

DO - 10.1016/j.biopsycho.2005.06.006

M3 - Article

C2 - 16098655

VL - 71

SP - 236

EP - 239

JO - Biological Psychology

JF - Biological Psychology

SN - 0301-0511

ER -