Selective recognition and electrochemical sensing of dopamine using a ferrocene-based heteroditopic receptor

Research output: Contribution to journalArticle

Authors

  • Hidekazu Miyaji
  • Haruka Komada
  • Keisuke Goto
  • Junko Fujimoto
  • Naoaki Kiriyama

Colleges, School and Institutes

Abstract

A redox-active ferrocene-based heteroditopic receptor bearing a boronic acid (as a catechol recognition site) and a benzo-18-crown-6-ether unit (as an ammonium ion recognition site) was synthesized. A 1:1 ditopic complex with dopamine was evidenced by mass spectrometry and NMR spectroscopy. Cyclic voltammetry measurements on the receptor in the presence of a series of organic guest species demonstrated the successful electrochemical sensing of dopamine through a distinct change in the ferrocene-centred redox-couple upon complex formation.

Details

Original languageEnglish
Pages (from-to)3853-3857
JournalTetrahedron Letters
Early online date11 Sep 2018
Publication statusPublished - 24 Oct 2018

Keywords

  • Electrochemical molecular sensor, Dopamine, Ferrocene, Boronic acid, Crown ether