Reward and punishment enhance motor adaptation in stroke

Research output: Contribution to journalArticle

Standard

Reward and punishment enhance motor adaptation in stroke. / Quattrocchi, Graziella; Greenwood, Richard; Rothwell, John C.; Galea, Joseph; Bestmann, Sven.

In: Journal of Neurology Neurosurgery and Psychiatry, Vol. 88, No. 9, 04.04.2017.

Research output: Contribution to journalArticle

Harvard

APA

Vancouver

Author

Quattrocchi, Graziella ; Greenwood, Richard ; Rothwell, John C. ; Galea, Joseph ; Bestmann, Sven. / Reward and punishment enhance motor adaptation in stroke. In: Journal of Neurology Neurosurgery and Psychiatry. 2017 ; Vol. 88, No. 9.

Bibtex

@article{d853a55cad314103b4441cd8df9e2223,
title = "Reward and punishment enhance motor adaptation in stroke",
abstract = "The effects of motor learning, such as motor adaptation, in stroke rehabilitation are often transient, thus mandating approaches that enhance the amount of learning and retention. Previously, we showed in young individuals that reward- and punishment-feedback have dissociable effects on motor adaptation, with punishment improving adaptation and reward enhancing retention. If these findings were able to generalise to stroke patients, they would provide a way to optimize motor learning in these patients. Therefore, we tested this in 45 chronic stroke patients allocated in three groups. Patients performed reaching movements with their paretic arm with a robotic manipulandum. After training (day 1), day 2 involved adapting to a novel force-field. During this adaptation phase, patients received performance-based feedback according to the group they were allocated: reward, punishment or no feedback (neutral). On day 3, patients readapted to the force-field but all groups now received neutral feedback. All patients adapted, with reward and punishment groups displaying greater adaptation and readaptation than the neutral group, irrespective of demographic, cognitive or functional differences. Remarkably, the reward and punishment groups adapted to similar degree as healthy controls. Finally, the reward group showed greater retention. This study provides, for the first time, evidence that reward and punishment can enhance motor adaptation in stroke patients. Further research on reinforcement-based motor learning regimes is warranted to translate these promising results into clinical practice and improve motor rehabilitation outcomes in stroke patients.",
keywords = "Adaptation, Motivation, Motor Learning, Reaching, Stroke",
author = "Graziella Quattrocchi and Richard Greenwood and Rothwell, {John C.} and Joseph Galea and Sven Bestmann",
year = "2017",
month = apr,
day = "4",
doi = "10.1136/jnnp-2016-314728",
language = "English",
volume = "88",
journal = "Journal of Neurology Neurosurgery and Psychiatry",
issn = "0022-3050",
publisher = "BMJ Publishing Group",
number = "9",

}

RIS

TY - JOUR

T1 - Reward and punishment enhance motor adaptation in stroke

AU - Quattrocchi, Graziella

AU - Greenwood, Richard

AU - Rothwell, John C.

AU - Galea, Joseph

AU - Bestmann, Sven

PY - 2017/4/4

Y1 - 2017/4/4

N2 - The effects of motor learning, such as motor adaptation, in stroke rehabilitation are often transient, thus mandating approaches that enhance the amount of learning and retention. Previously, we showed in young individuals that reward- and punishment-feedback have dissociable effects on motor adaptation, with punishment improving adaptation and reward enhancing retention. If these findings were able to generalise to stroke patients, they would provide a way to optimize motor learning in these patients. Therefore, we tested this in 45 chronic stroke patients allocated in three groups. Patients performed reaching movements with their paretic arm with a robotic manipulandum. After training (day 1), day 2 involved adapting to a novel force-field. During this adaptation phase, patients received performance-based feedback according to the group they were allocated: reward, punishment or no feedback (neutral). On day 3, patients readapted to the force-field but all groups now received neutral feedback. All patients adapted, with reward and punishment groups displaying greater adaptation and readaptation than the neutral group, irrespective of demographic, cognitive or functional differences. Remarkably, the reward and punishment groups adapted to similar degree as healthy controls. Finally, the reward group showed greater retention. This study provides, for the first time, evidence that reward and punishment can enhance motor adaptation in stroke patients. Further research on reinforcement-based motor learning regimes is warranted to translate these promising results into clinical practice and improve motor rehabilitation outcomes in stroke patients.

AB - The effects of motor learning, such as motor adaptation, in stroke rehabilitation are often transient, thus mandating approaches that enhance the amount of learning and retention. Previously, we showed in young individuals that reward- and punishment-feedback have dissociable effects on motor adaptation, with punishment improving adaptation and reward enhancing retention. If these findings were able to generalise to stroke patients, they would provide a way to optimize motor learning in these patients. Therefore, we tested this in 45 chronic stroke patients allocated in three groups. Patients performed reaching movements with their paretic arm with a robotic manipulandum. After training (day 1), day 2 involved adapting to a novel force-field. During this adaptation phase, patients received performance-based feedback according to the group they were allocated: reward, punishment or no feedback (neutral). On day 3, patients readapted to the force-field but all groups now received neutral feedback. All patients adapted, with reward and punishment groups displaying greater adaptation and readaptation than the neutral group, irrespective of demographic, cognitive or functional differences. Remarkably, the reward and punishment groups adapted to similar degree as healthy controls. Finally, the reward group showed greater retention. This study provides, for the first time, evidence that reward and punishment can enhance motor adaptation in stroke patients. Further research on reinforcement-based motor learning regimes is warranted to translate these promising results into clinical practice and improve motor rehabilitation outcomes in stroke patients.

KW - Adaptation

KW - Motivation

KW - Motor Learning

KW - Reaching

KW - Stroke

UR - http://biorxiv.org/content/early/2017/02/06/106377

U2 - 10.1136/jnnp-2016-314728

DO - 10.1136/jnnp-2016-314728

M3 - Article

VL - 88

JO - Journal of Neurology Neurosurgery and Psychiatry

JF - Journal of Neurology Neurosurgery and Psychiatry

SN - 0022-3050

IS - 9

ER -