Resource utilisation associated with single digit Dupuytren's contracture treated with either surgery or injection of collagenase Clostridium histolyticum

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Colleges, School and Institutes


The gold standard treatment for Dupuytren's contracture is surgical excision of the cord. A non-surgical treatment with collagenase clostridium histolyticum injection is available but appears costly.

Objectives: To provide data on resource consumption related to surgical and non-surgical treatment for Dupuytren's contracture.

Design and Participants: Twenty patients with a single digit Dupuytren's contracture, 10 treated with surgical excision, and 10 treated with a single injection of collagenase.

Measurements: Minutes spent in theatre, number of follow-up appointments, time to skin healing, and patients return to normal activities of daily living.

Results: The injection group was significantly better regarding theatre time (p < 0.0001), follow-up appointments (p = 0.048), skin healing time (p < 0.001), and return to normal activities of daily living (p = 0.02) than the operated group.

Conclusions: There are significant personal and health economic differences between the two methods of treatment which may influence local choice.


Original languageEnglish
Pages (from-to)205-209
Number of pages5
JournalHand surgery : an international journal devoted to hand and upper limb surgery and related research : journal of the Asia-Pacific Federation of Societies for Surgery of the Hand
Issue number02
Publication statusPublished - 2014


  • Resources, Dupuytren's Contracture, Surgery, Injection, Xiapex