Repeat-element driven activation of proto-oncogenes in human malignancies
Research output: Contribution to journal › Article
Colleges, School and Institutes
Recent data demonstrated that the aberrant activity of endogenous repetitive elements of the DNA in humans can drive the expression of proto-oncogenes. This article summarizes these results and gives an outlook on the impact of these findings on the pathogenesis and therapy of human cancer.
|Number of pages||6|
|Publication status||Published - 1 Nov 2010|
- DNA methylation, LTR, Hodgkin lymphoma, epigenetic reprogramming, CSF-1 receptor