Relieving phantom limb pain with multimodal sensory-motor training

Research output: Contribution to journalArticlepeer-review

Standard

Relieving phantom limb pain with multimodal sensory-motor training. / De Nunzio, Alessandro Marco; Schweisfurth, Meike Annika; Ge, Nan; Falla, Deborah; Hahne, Janne Mathias; Gödecke, Kim; Petzke, Frank; Siebertz, Mathias; Dechent, Peter; Weiss, Thomas; Flor, Herta; Graimann, Bernhard; Aszmann, Oskar; Farina, Dario.

In: Journal of Neural Engineering, Vol. 15, 066022, 16.10.2018.

Research output: Contribution to journalArticlepeer-review

Harvard

De Nunzio, AM, Schweisfurth, MA, Ge, N, Falla, D, Hahne, JM, Gödecke, K, Petzke, F, Siebertz, M, Dechent, P, Weiss, T, Flor, H, Graimann, B, Aszmann, O & Farina, D 2018, 'Relieving phantom limb pain with multimodal sensory-motor training', Journal of Neural Engineering, vol. 15, 066022. https://doi.org/10.1088/1741-2552/aae271

APA

De Nunzio, A. M., Schweisfurth, M. A., Ge, N., Falla, D., Hahne, J. M., Gödecke, K., Petzke, F., Siebertz, M., Dechent, P., Weiss, T., Flor, H., Graimann, B., Aszmann, O., & Farina, D. (2018). Relieving phantom limb pain with multimodal sensory-motor training. Journal of Neural Engineering, 15, [066022]. https://doi.org/10.1088/1741-2552/aae271

Vancouver

Author

De Nunzio, Alessandro Marco ; Schweisfurth, Meike Annika ; Ge, Nan ; Falla, Deborah ; Hahne, Janne Mathias ; Gödecke, Kim ; Petzke, Frank ; Siebertz, Mathias ; Dechent, Peter ; Weiss, Thomas ; Flor, Herta ; Graimann, Bernhard ; Aszmann, Oskar ; Farina, Dario. / Relieving phantom limb pain with multimodal sensory-motor training. In: Journal of Neural Engineering. 2018 ; Vol. 15.

Bibtex

@article{09932cca84284d718f6b64a0ac0c58fe,
title = "Relieving phantom limb pain with multimodal sensory-motor training",
abstract = "Background: The causes for the disabling condition of phantom limb pain (PLP), affecting 85% of amputees, are so far unknown, with few effective treatments available. Sensory feedback based strategies to normalize the motor commands to control the phantom limb offer important targets for new effective treatments as the correlation between phantom limb motor control and sensory feedback from the motor intention has been identified as a possible mechanism for PLP development.Methods: Ten upper-limb amputees, suffering from chronic PLP, underwent 16 days of intensive training on phantom-limb movement control. Visual and tactile feedback, driven by muscular activity at the stump, was provided with the aim of reducing PLP intensity. Results: A 32.1% reduction of PLP intensity was obtained at the follow-up (6 weeks after the end of the training, with an initial 21.6% reduction immediately at the end of the training) reaching clinical effectiveness for chronic pain reduction.Conclusion: Multimodal sensory-motor training on phantom-limb movements with visual and tactile feedback is a new method for PLP reduction.Significance: The study results revealed a substantial reduction in phantom limb pain intensity, obtained with a new training protocol focused on improving phantom limb motor output using visual and tactile feedback from the stump muscular activity executed to move the phantom limb.",
keywords = "Motor Training, Phantom Limb Pain, Sensory Feedback",
author = "{De Nunzio}, {Alessandro Marco} and Schweisfurth, {Meike Annika} and Nan Ge and Deborah Falla and Hahne, {Janne Mathias} and Kim G{\"o}decke and Frank Petzke and Mathias Siebertz and Peter Dechent and Thomas Weiss and Herta Flor and Bernhard Graimann and Oskar Aszmann and Dario Farina",
note = "{\textcopyright} 2018 IOP Publishing Ltd.",
year = "2018",
month = oct,
day = "16",
doi = "10.1088/1741-2552/aae271",
language = "English",
volume = "15",
journal = "Journal of Neural Engineering",
issn = "1741-2560",
publisher = "IOP Publishing",

}

RIS

TY - JOUR

T1 - Relieving phantom limb pain with multimodal sensory-motor training

AU - De Nunzio, Alessandro Marco

AU - Schweisfurth, Meike Annika

AU - Ge, Nan

AU - Falla, Deborah

AU - Hahne, Janne Mathias

AU - Gödecke, Kim

AU - Petzke, Frank

AU - Siebertz, Mathias

AU - Dechent, Peter

AU - Weiss, Thomas

AU - Flor, Herta

AU - Graimann, Bernhard

AU - Aszmann, Oskar

AU - Farina, Dario

N1 - © 2018 IOP Publishing Ltd.

PY - 2018/10/16

Y1 - 2018/10/16

N2 - Background: The causes for the disabling condition of phantom limb pain (PLP), affecting 85% of amputees, are so far unknown, with few effective treatments available. Sensory feedback based strategies to normalize the motor commands to control the phantom limb offer important targets for new effective treatments as the correlation between phantom limb motor control and sensory feedback from the motor intention has been identified as a possible mechanism for PLP development.Methods: Ten upper-limb amputees, suffering from chronic PLP, underwent 16 days of intensive training on phantom-limb movement control. Visual and tactile feedback, driven by muscular activity at the stump, was provided with the aim of reducing PLP intensity. Results: A 32.1% reduction of PLP intensity was obtained at the follow-up (6 weeks after the end of the training, with an initial 21.6% reduction immediately at the end of the training) reaching clinical effectiveness for chronic pain reduction.Conclusion: Multimodal sensory-motor training on phantom-limb movements with visual and tactile feedback is a new method for PLP reduction.Significance: The study results revealed a substantial reduction in phantom limb pain intensity, obtained with a new training protocol focused on improving phantom limb motor output using visual and tactile feedback from the stump muscular activity executed to move the phantom limb.

AB - Background: The causes for the disabling condition of phantom limb pain (PLP), affecting 85% of amputees, are so far unknown, with few effective treatments available. Sensory feedback based strategies to normalize the motor commands to control the phantom limb offer important targets for new effective treatments as the correlation between phantom limb motor control and sensory feedback from the motor intention has been identified as a possible mechanism for PLP development.Methods: Ten upper-limb amputees, suffering from chronic PLP, underwent 16 days of intensive training on phantom-limb movement control. Visual and tactile feedback, driven by muscular activity at the stump, was provided with the aim of reducing PLP intensity. Results: A 32.1% reduction of PLP intensity was obtained at the follow-up (6 weeks after the end of the training, with an initial 21.6% reduction immediately at the end of the training) reaching clinical effectiveness for chronic pain reduction.Conclusion: Multimodal sensory-motor training on phantom-limb movements with visual and tactile feedback is a new method for PLP reduction.Significance: The study results revealed a substantial reduction in phantom limb pain intensity, obtained with a new training protocol focused on improving phantom limb motor output using visual and tactile feedback from the stump muscular activity executed to move the phantom limb.

KW - Motor Training

KW - Phantom Limb Pain

KW - Sensory Feedback

U2 - 10.1088/1741-2552/aae271

DO - 10.1088/1741-2552/aae271

M3 - Article

C2 - 30229747

VL - 15

JO - Journal of Neural Engineering

JF - Journal of Neural Engineering

SN - 1741-2560

M1 - 066022

ER -