Relieving phantom limb pain with multimodal sensory-motor training
Research output: Contribution to journal › Article › peer-review
Colleges, School and Institutes
- Faculty of Life Sciences, Hochschule für Angewandte Wissenschaften, Hamburg, Hamburg, GERMANY.
- Neurorehabilitation Systems Research Group, Department of Trauma Surgery, Orthopedic Surgery and Hand Surger, University Medical Center Göttingen, Göttingen, GERMANY.
- Trauma Surgery, Orthopedic Surgery and Hand Surgery, Universitätsmedizin Göttingen, Göttingen, GERMANY.
- University Hospital Göttingen
- MR research in neurology and psychiatry, Cognitive Neurology, University Medical Center Göttingen, Georg-August University, Göttingen, Göttingen, GERMANY.
- Department of Biological and Clinical Psychology, Institute of Psychology, Friedrich Schiller University, Jena, GERMANY.
- Zentralinstitut fur Seelische Gesundheit, Mannheim, 68072, GERMANY.
- Department of Translational Research and Knowledge Management, Otto Bock HealthCare GmbH, Max-Näder-Straße 15, 37115, Duderstadt, Germany.
- Division of Plastic and Reconstructive Surgery, Department of Surgery, Medical University of Vienna, Vienna, AUSTRIA.
- Imperial College London
Background: The causes for the disabling condition of phantom limb pain (PLP), affecting 85% of amputees, are so far unknown, with few effective treatments available. Sensory feedback based strategies to normalize the motor commands to control the phantom limb offer important targets for new effective treatments as the correlation between phantom limb motor control and sensory feedback from the motor intention has been identified as a possible mechanism for PLP development.
Methods: Ten upper-limb amputees, suffering from chronic PLP, underwent 16 days of intensive training on phantom-limb movement control. Visual and tactile feedback, driven by muscular activity at the stump, was provided with the aim of reducing PLP intensity.
Results: A 32.1% reduction of PLP intensity was obtained at the follow-up (6 weeks after the end of the training, with an initial 21.6% reduction immediately at the end of the training) reaching clinical effectiveness for chronic pain reduction.
Conclusion: Multimodal sensory-motor training on phantom-limb movements with visual and tactile feedback is a new method for PLP reduction.
Significance: The study results revealed a substantial reduction in phantom limb pain intensity, obtained with a new training protocol focused on improving phantom limb motor output using visual and tactile feedback from the stump muscular activity executed to move the phantom limb.
|Journal||Journal of Neural Engineering|
|Early online date||19 Sep 2018|
|Publication status||Published - 16 Oct 2018|
- Motor Training, Phantom Limb Pain, Sensory Feedback