Release of diacylglycerol-enriched vesicles from erythrocytes with increased intracellular [Ca2+]
Research output: Contribution to journal › Article
- Department of Biochemistry
- Birmingham University
WHEN the intracellular Ca2+ concentration of human red cells was increased by treatment of the cells with A23187, a divalent cation ionophore, they changed shape from discocyte to echinocyte1-3 and the 1,2-diacylglycerol content of their membranes was increased2-4. In these experiments it seemed that microvesicles budded off from the microvillus-like projections on the echinocytes2,3. We have now isolated the microvesicles and examined their composition and structure.
|Number of pages||3|
|Publication status||Published - 1 Dec 1976|