Recruitment of RNA polymerase to Class II CRP-dependent promoters is improved by a second upstream-bound CRP molecule

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@article{753e44b12843465da99cb8751fa6b775,
title = "Recruitment of RNA polymerase to Class II CRP-dependent promoters is improved by a second upstream-bound CRP molecule",
abstract = "Genetics and biochemistry have been exploited to investigate transcription activation by the Escherichia coli CRP (cAMP receptor protein) factor at promoters with a DNA site for CRP near position -41 and the effects of a second upstream-bound CRP molecule. We show that the upstream-bound CRP contributes to transcription activation by improving the recruitment of RNA polymerase.",
keywords = "cAMP receptor protein (CRP), RNA polymerase, recruitment, activation of transcription, kinetic analysis, transcription",
author = "Nora Miroslavova and Jennie Mitchell and J Tebbutt and Stephen Busby",
year = "2006",
month = dec,
day = "1",
doi = "10.1042/BST0341075",
language = "English",
volume = "34",
pages = "1075--1078",
journal = "Biochemical Society Transactions",
issn = "1470-8752",
publisher = "Portland Press",
number = "6",

}

RIS

TY - JOUR

T1 - Recruitment of RNA polymerase to Class II CRP-dependent promoters is improved by a second upstream-bound CRP molecule

AU - Miroslavova, Nora

AU - Mitchell, Jennie

AU - Tebbutt, J

AU - Busby, Stephen

PY - 2006/12/1

Y1 - 2006/12/1

N2 - Genetics and biochemistry have been exploited to investigate transcription activation by the Escherichia coli CRP (cAMP receptor protein) factor at promoters with a DNA site for CRP near position -41 and the effects of a second upstream-bound CRP molecule. We show that the upstream-bound CRP contributes to transcription activation by improving the recruitment of RNA polymerase.

AB - Genetics and biochemistry have been exploited to investigate transcription activation by the Escherichia coli CRP (cAMP receptor protein) factor at promoters with a DNA site for CRP near position -41 and the effects of a second upstream-bound CRP molecule. We show that the upstream-bound CRP contributes to transcription activation by improving the recruitment of RNA polymerase.

KW - cAMP receptor protein (CRP)

KW - RNA polymerase

KW - recruitment

KW - activation of transcription

KW - kinetic analysis

KW - transcription

UR - http://www.scopus.com/inward/record.url?scp=34248656233&partnerID=8YFLogxK

U2 - 10.1042/BST0341075

DO - 10.1042/BST0341075

M3 - Article

C2 - 17073754

VL - 34

SP - 1075

EP - 1078

JO - Biochemical Society Transactions

JF - Biochemical Society Transactions

SN - 1470-8752

IS - 6

ER -