Abstract
Genetics and biochemistry have been exploited to investigate transcription activation by the Escherichia coli CRP (cAMP receptor protein) factor at promoters with a DNA site for CRP near position -41 and the effects of a second upstream-bound CRP molecule. We show that the upstream-bound CRP contributes to transcription activation by improving the recruitment of RNA polymerase.
Original language | English |
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Pages (from-to) | 1075-1078 |
Number of pages | 4 |
Journal | Biochemical Society Transactions |
Volume | 34 |
Issue number | 6 |
DOIs | |
Publication status | Published - 1 Dec 2006 |
Keywords
- cAMP receptor protein (CRP)
- RNA polymerase
- recruitment
- activation of transcription
- kinetic analysis
- transcription