Recent advances in designed coiled coils and helical bundles with inorganic prosthetic groups - from structural to functional applications
Research output: Contribution to journal › Review article › peer-review
Colleges, School and Institutes
Recent contributions to the de novo design of metalloproteins based on coiled coils and helical bundles are described herein, with examples covering mononuclear, multinuclear, and metallo-porphyrin sites, as well as membrane soluble designs. Important progress is being made in the field with a diverse range of functionalities, sometimes beyond those found in biology, being successfully engineered into these simplified scaffolds and represents an exciting prospect for the future.
|Number of pages||6|
|Journal||Current Opinion in Chemical Biology|
|Early online date||28 Mar 2016|
|Publication status||Published - 1 Apr 2016|