Rating papilloedema: an evaluation of the Frisén classification in idiopathic intracranial hypertension.

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Rating papilloedema: an evaluation of the Frisén classification in idiopathic intracranial hypertension. / Sinclair, Alexandra; Burdon, MA; Nightingale, Peter; Matthews, TD; Jacks, A; Lawden, M; Sivaguru, A; Gaskin, BJ; Rauz, Saaeha; Clarke, Carl; Ball, AK.

In: Journal of Neurology, 12.01.2012.

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@article{e56e9d98770c4b77bb4e5fc4807b5175,
title = "Rating papilloedema: an evaluation of the Fris{\'e}n classification in idiopathic intracranial hypertension.",
abstract = "The appearance of the optic disc is a key measure of disease status in idiopathic intracranial hypertension (IIH). The Fris{\'e}n classification describes stages of optic disc swelling (grades 0-5). It is the only classification of papilloedema, and is used internationally in clinical and research practice. Despite this, there has been very limited evaluation of the scale. We assessed the inter-rater reproducibility and ability to discriminate optic disc changes over time using the Fris{\'e}n classification compared with a system of ranking papilloedema severity in patients with IIH. Paired disc photographs (before and after treatment) were obtained from 47 patients with IIH (25 acute and 22 chronic). Six neuro-ophthalmologists blinded to patient identity, clinical information and chronology of the photographs reviewed the discs and allocated a Fris{\'e}n grade and ranked the paired discs in order of papilloedema severity (disc ranking). A total of 188 optic disc photographs were reviewed. All six reviewers agreed in only three comparisons (1.6%) when using the Fris{\'e}n classification, compared with 42 comparisons (45.2%) when using disc ranking. The probability of agreement between any two reviewers was 36.1% for Fris{\'e}n grade and 70.0% for disc ranking. Disc ranking had significantly greater sensitivity for finding differences in degree of disc oedema, identifying a difference in 75.3% of paired photographs compared to 53.2% detected using the Fris{\'e}n classification (p ",
author = "Alexandra Sinclair and MA Burdon and Peter Nightingale and TD Matthews and A Jacks and M Lawden and A Sivaguru and BJ Gaskin and Saaeha Rauz and Carl Clarke and AK Ball",
year = "2012",
month = jan,
day = "12",
doi = "10.1007/s00415-011-6365-6",
language = "English",
journal = "Journal of Neurology",
issn = "0340-5354",
publisher = "Springer",

}

RIS

TY - JOUR

T1 - Rating papilloedema: an evaluation of the Frisén classification in idiopathic intracranial hypertension.

AU - Sinclair, Alexandra

AU - Burdon, MA

AU - Nightingale, Peter

AU - Matthews, TD

AU - Jacks, A

AU - Lawden, M

AU - Sivaguru, A

AU - Gaskin, BJ

AU - Rauz, Saaeha

AU - Clarke, Carl

AU - Ball, AK

PY - 2012/1/12

Y1 - 2012/1/12

N2 - The appearance of the optic disc is a key measure of disease status in idiopathic intracranial hypertension (IIH). The Frisén classification describes stages of optic disc swelling (grades 0-5). It is the only classification of papilloedema, and is used internationally in clinical and research practice. Despite this, there has been very limited evaluation of the scale. We assessed the inter-rater reproducibility and ability to discriminate optic disc changes over time using the Frisén classification compared with a system of ranking papilloedema severity in patients with IIH. Paired disc photographs (before and after treatment) were obtained from 47 patients with IIH (25 acute and 22 chronic). Six neuro-ophthalmologists blinded to patient identity, clinical information and chronology of the photographs reviewed the discs and allocated a Frisén grade and ranked the paired discs in order of papilloedema severity (disc ranking). A total of 188 optic disc photographs were reviewed. All six reviewers agreed in only three comparisons (1.6%) when using the Frisén classification, compared with 42 comparisons (45.2%) when using disc ranking. The probability of agreement between any two reviewers was 36.1% for Frisén grade and 70.0% for disc ranking. Disc ranking had significantly greater sensitivity for finding differences in degree of disc oedema, identifying a difference in 75.3% of paired photographs compared to 53.2% detected using the Frisén classification (p 

AB - The appearance of the optic disc is a key measure of disease status in idiopathic intracranial hypertension (IIH). The Frisén classification describes stages of optic disc swelling (grades 0-5). It is the only classification of papilloedema, and is used internationally in clinical and research practice. Despite this, there has been very limited evaluation of the scale. We assessed the inter-rater reproducibility and ability to discriminate optic disc changes over time using the Frisén classification compared with a system of ranking papilloedema severity in patients with IIH. Paired disc photographs (before and after treatment) were obtained from 47 patients with IIH (25 acute and 22 chronic). Six neuro-ophthalmologists blinded to patient identity, clinical information and chronology of the photographs reviewed the discs and allocated a Frisén grade and ranked the paired discs in order of papilloedema severity (disc ranking). A total of 188 optic disc photographs were reviewed. All six reviewers agreed in only three comparisons (1.6%) when using the Frisén classification, compared with 42 comparisons (45.2%) when using disc ranking. The probability of agreement between any two reviewers was 36.1% for Frisén grade and 70.0% for disc ranking. Disc ranking had significantly greater sensitivity for finding differences in degree of disc oedema, identifying a difference in 75.3% of paired photographs compared to 53.2% detected using the Frisén classification (p 

U2 - 10.1007/s00415-011-6365-6

DO - 10.1007/s00415-011-6365-6

M3 - Article

C2 - 22237821

JO - Journal of Neurology

JF - Journal of Neurology

SN - 0340-5354

ER -