Rapid interrogation of the physical and chemical characteristics of salbutamol sulphate aerosol from a pressurised metered-dose inhaler (pMDI)

Research output: Contribution to journalArticlepeer-review

Authors

  • H.-j. Tong
  • C. Fitzgerald
  • P. J. Gallimore
  • M. Kalberer
  • M. K. Kuimova
  • A. D. Ward

Colleges, School and Institutes

Abstract

Individual micron-sized solid particles from a Salamol® pharmaceutical inhaler are stably captured in air using an optical trap for the first time. Raman spectroscopy of the levitated particles allows online interrogation of composition and deliquescent phase change within a high humidity environment that mimics the particle's travel from inhaler to lung.

Details

Original languageEnglish
Pages (from-to)15499-15502
JournalChemical Communications
Volume50
Issue number98
Publication statusPublished - 6 Oct 2014