Pulse wave velocity in South African women and children: comparison between the Mobil-O-Graph and SphygmoCor XCEL devices

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Pulse wave velocity in South African women and children : comparison between the Mobil-O-Graph and SphygmoCor XCEL devices. / KOLKENBECK-RUH, Andrea ; SOEPNEL, Larske ; KIM, Andrew Wooyoung ; NAIDOO, Sanushka ; SMITH, Wayne ; Davies, Justine; WARE, Lisa Jayne .

In: Journal of Hypertension, 16.07.2021.

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KOLKENBECK-RUH, Andrea ; SOEPNEL, Larske ; KIM, Andrew Wooyoung ; NAIDOO, Sanushka ; SMITH, Wayne ; Davies, Justine ; WARE, Lisa Jayne . / Pulse wave velocity in South African women and children : comparison between the Mobil-O-Graph and SphygmoCor XCEL devices. In: Journal of Hypertension. 2021.

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@article{d90a2fb637354822ae13bc17df8308e1,
title = "Pulse wave velocity in South African women and children: comparison between the Mobil-O-Graph and SphygmoCor XCEL devices",
abstract = "Background: Carotid-femoral pulse wave velocity (PWV) is the gold-standard non-invasive measure of arterial stiffness. Data comparing tonometry-based devices such as the SphygmoCor XCEL to simpler brachial-cuff-based estimates of PWV, such as from the Mobil-O-Graph in African populations is sparse. We therefore aimed to compare PWV measured by the Mobil-O-Graph and the SphygmoCor XCEL device in a sample of South African women and children. Methods: Women (n=85) 29 years (IQR:29-69) and their children/grandchildren (n=27) 7 years (IQR:4-11) were recruited for PWV measurement with Mobil-O-Graph and SphygmoCor XCEL on the same day. Wilcoxon signed-rank test, regression analysis, spearman correlation and Bland-Altman plots were used for PWV comparison between devices. Results: For adults, the SphygmoCor XCEL device had a significantly higher PWV (7.3m/s, IQR:6.4-8.5) compared to the Mobil-O-Graph (5.9m/s,IQR:5.0-8.1,p=0.001) with a correlation coefficient of 0.809 (p=<0.001). Bland-Altman analysis indicated an acceptable level of agreement but significant bias (mean difference PWV:0.90±1.02m/s; limits of agreement:-1.10 to 2.90). The odds of having a PWV difference >1m/s decreased with a higher age (OR:0.95, 95%CI=0.92-0.98) and increased with greater height (OR:1.10,95%CI=1.01-1.21,p=0.03) in multivariable analysis. In children, the Bland-Altman indicated an excellent level of agreement (-0.03±0.63m/s; limits of agreement:-1.26 to 1.21), but no correlation was found (rs=0.08,p=0.71).Conclusion: Particularly in younger and taller women, the Mobil-O-Graph significantly underestimated PWV compared to the SphygmoCor. While no correlation was found between the two devices for children, further research is required due to the small sample size. Furthermore, the clinical value of both methods in young African populations requires further investigation. Keywords: pulse wave analysis; vascular stiffness; cardiovascular diagnostic technique; Sub-Saharan Africa; child health; women{\textquoteright}s health",
keywords = "cardiovascular diagnostic technique, child health, pulse wave analysis, sub-saharan Africa, vascular stiffness, women's health",
author = "Andrea KOLKENBECK-RUH and Larske SOEPNEL and KIM, {Andrew Wooyoung} and Sanushka NAIDOO and Wayne SMITH and Justine Davies and WARE, {Lisa Jayne}",
year = "2021",
month = jul,
day = "16",
doi = "10.1097/HJH.0000000000002976",
language = "English",
journal = "Journal of Hypertension",
issn = "0263-6352",
publisher = "Lippincott Williams and Wilkins",

}

RIS

TY - JOUR

T1 - Pulse wave velocity in South African women and children

T2 - comparison between the Mobil-O-Graph and SphygmoCor XCEL devices

AU - KOLKENBECK-RUH, Andrea

AU - SOEPNEL, Larske

AU - KIM, Andrew Wooyoung

AU - NAIDOO, Sanushka

AU - SMITH, Wayne

AU - Davies, Justine

AU - WARE, Lisa Jayne

PY - 2021/7/16

Y1 - 2021/7/16

N2 - Background: Carotid-femoral pulse wave velocity (PWV) is the gold-standard non-invasive measure of arterial stiffness. Data comparing tonometry-based devices such as the SphygmoCor XCEL to simpler brachial-cuff-based estimates of PWV, such as from the Mobil-O-Graph in African populations is sparse. We therefore aimed to compare PWV measured by the Mobil-O-Graph and the SphygmoCor XCEL device in a sample of South African women and children. Methods: Women (n=85) 29 years (IQR:29-69) and their children/grandchildren (n=27) 7 years (IQR:4-11) were recruited for PWV measurement with Mobil-O-Graph and SphygmoCor XCEL on the same day. Wilcoxon signed-rank test, regression analysis, spearman correlation and Bland-Altman plots were used for PWV comparison between devices. Results: For adults, the SphygmoCor XCEL device had a significantly higher PWV (7.3m/s, IQR:6.4-8.5) compared to the Mobil-O-Graph (5.9m/s,IQR:5.0-8.1,p=0.001) with a correlation coefficient of 0.809 (p=<0.001). Bland-Altman analysis indicated an acceptable level of agreement but significant bias (mean difference PWV:0.90±1.02m/s; limits of agreement:-1.10 to 2.90). The odds of having a PWV difference >1m/s decreased with a higher age (OR:0.95, 95%CI=0.92-0.98) and increased with greater height (OR:1.10,95%CI=1.01-1.21,p=0.03) in multivariable analysis. In children, the Bland-Altman indicated an excellent level of agreement (-0.03±0.63m/s; limits of agreement:-1.26 to 1.21), but no correlation was found (rs=0.08,p=0.71).Conclusion: Particularly in younger and taller women, the Mobil-O-Graph significantly underestimated PWV compared to the SphygmoCor. While no correlation was found between the two devices for children, further research is required due to the small sample size. Furthermore, the clinical value of both methods in young African populations requires further investigation. Keywords: pulse wave analysis; vascular stiffness; cardiovascular diagnostic technique; Sub-Saharan Africa; child health; women’s health

AB - Background: Carotid-femoral pulse wave velocity (PWV) is the gold-standard non-invasive measure of arterial stiffness. Data comparing tonometry-based devices such as the SphygmoCor XCEL to simpler brachial-cuff-based estimates of PWV, such as from the Mobil-O-Graph in African populations is sparse. We therefore aimed to compare PWV measured by the Mobil-O-Graph and the SphygmoCor XCEL device in a sample of South African women and children. Methods: Women (n=85) 29 years (IQR:29-69) and their children/grandchildren (n=27) 7 years (IQR:4-11) were recruited for PWV measurement with Mobil-O-Graph and SphygmoCor XCEL on the same day. Wilcoxon signed-rank test, regression analysis, spearman correlation and Bland-Altman plots were used for PWV comparison between devices. Results: For adults, the SphygmoCor XCEL device had a significantly higher PWV (7.3m/s, IQR:6.4-8.5) compared to the Mobil-O-Graph (5.9m/s,IQR:5.0-8.1,p=0.001) with a correlation coefficient of 0.809 (p=<0.001). Bland-Altman analysis indicated an acceptable level of agreement but significant bias (mean difference PWV:0.90±1.02m/s; limits of agreement:-1.10 to 2.90). The odds of having a PWV difference >1m/s decreased with a higher age (OR:0.95, 95%CI=0.92-0.98) and increased with greater height (OR:1.10,95%CI=1.01-1.21,p=0.03) in multivariable analysis. In children, the Bland-Altman indicated an excellent level of agreement (-0.03±0.63m/s; limits of agreement:-1.26 to 1.21), but no correlation was found (rs=0.08,p=0.71).Conclusion: Particularly in younger and taller women, the Mobil-O-Graph significantly underestimated PWV compared to the SphygmoCor. While no correlation was found between the two devices for children, further research is required due to the small sample size. Furthermore, the clinical value of both methods in young African populations requires further investigation. Keywords: pulse wave analysis; vascular stiffness; cardiovascular diagnostic technique; Sub-Saharan Africa; child health; women’s health

KW - cardiovascular diagnostic technique

KW - child health

KW - pulse wave analysis

KW - sub-saharan Africa

KW - vascular stiffness

KW - women's health

U2 - 10.1097/HJH.0000000000002976

DO - 10.1097/HJH.0000000000002976

M3 - Article

JO - Journal of Hypertension

JF - Journal of Hypertension

SN - 0263-6352

ER -