Pulmonary lymphangioleiomyomatosis masquerading as unilateral heterogeneous emphysema

Research output: Contribution to journalArticlepeer-review

Authors

  • Lakshmi Srinivasan
  • Saifullah Mohamed
  • Akshay Patel
  • Khurum Mazhar
  • Shilajit Ghosh

Colleges, School and Institutes

External organisations

  • Royal Stoke University Hospital

Abstract

Pulmonary lymphangioleiomyomatosis (LAM) is a rare, well-described pathology and usually is exclusive to females of a reproductive age. We present a 45 year-old lady who presented to the surgeons 1 year after an admission with acute dyspnoea following influenza infection. Initial computed tomography imaging findings demonstrated severe, heterogenous right-sided bullous emphysematous changes, but histopathological analysis of the post-operative specimen favoured a diagnosis of LAM. This case demonstrates the importance of considering LAM as a differential diagnosis for findings of unilateral emphysema or lobar emphysema, in which alpha 1-antitrypsin deficiency has been excluded and in those without a significant smoking history.

Details

Original languageEnglish
Article numberrjaa486
JournalJournal of Surgical Case Reports
Volume2020
Issue number11
Early online date30 Nov 2020
Publication statusPublished - Nov 2020