Proteomic analysis of resectable non-small cell lung cancer: post resection serum samples may be useful in identifying potential markers.

Sridhar Rathinam; Douglas Ward; Nicholas James; Pala Rajesh

doi:10.1510/icvts.2010.260166

Proteomic analysis of resectable non-small cell lung cancer: post resection serum samples may be useful in identifying potential markers.

Sridhar Rathinam, Douglas Ward, Nicholas James, Pala Rajesh

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Abstract

Surface-enhanced laser desorptionyionisation time-of-flight mass spectrometry (SELDI-TOF-MS) can be used to analyse peptides and proteins in clinical samples. A prospective study was undertaken on patients undergoing curative resection for non-small cell lung cancer (NSCLC): we used SELDI-TOF-MS to compare the proteomic profiles of serum from these patients both before surgical resection and after resection (disease-free) to identify potential biomarkers. Student t-tests were used, and a P-value of

Original language	English
Pages (from-to)	3-6
Number of pages	4
Journal	Interactive CardioVascular and Thoracic Surgery
Volume	13
Issue number	1
DOIs	https://doi.org/10.1510/icvts.2010.260166
Publication status	Published - 27 Apr 2011

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10.1510/icvts.2010.260166

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Proteomic analysis of resectable non-small cell lung cancer: post resection serum samples may be useful in identifying potential markers.

Abstract

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