Protein kinase Cε and protein kinase Cθ double-deficient mice have a bleeding diathesis

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Colleges, School and Institutes


In comparison to the classical isoforms of protein kinase C (PKC), the novel isoforms are thought to play minor or inhibitory roles in the regulation of platelet activation and thrombosis.


Original languageEnglish
Pages (from-to)1887-94
Number of pages8
JournalJournal of thrombosis and haemostasis : JTH
Issue number9
Publication statusPublished - 2012