TY - JOUR
T1 - Prostate-specific antigen levels in patients receiving long-term dialysis
AU - Harper, Lorraine
AU - MacIntyre, CW
AU - Macdougall, IC
AU - Raine, AEG
AU - Baker, LRI
PY - 1995/10/1
Y1 - 1995/10/1
N2 - OBJECTIVE: To investigate the effect, if any, of renal failure upon prostate-specific antigen (PSA) levels and the validity of PSA estimation as a marker of prostatic disease in renal failure. PATIENTS AND METHODS: PSA was measured in 65 men (median age 67 years, range 39-84) on regular haemodialysis and 37 men (median age 70 years, range 42-77) on continuous ambulatory peritoneal dialysis (CAPD). Patients with a PSA level > 4 ng/mL underwent prostatic biopsy guided by transrectal ultrasonography. RESULTS: There was no evidence of an artefactual elevation of PSA attributable solely to renal failure. All eight patients with a PSA level > 4 ng/mL had prostatic disease. CONCLUSION: PSA measurements in patients with end-stage renal failure treated by dialysis remain a useful marker of prostatic disease.
AB - OBJECTIVE: To investigate the effect, if any, of renal failure upon prostate-specific antigen (PSA) levels and the validity of PSA estimation as a marker of prostatic disease in renal failure. PATIENTS AND METHODS: PSA was measured in 65 men (median age 67 years, range 39-84) on regular haemodialysis and 37 men (median age 70 years, range 42-77) on continuous ambulatory peritoneal dialysis (CAPD). Patients with a PSA level > 4 ng/mL underwent prostatic biopsy guided by transrectal ultrasonography. RESULTS: There was no evidence of an artefactual elevation of PSA attributable solely to renal failure. All eight patients with a PSA level > 4 ng/mL had prostatic disease. CONCLUSION: PSA measurements in patients with end-stage renal failure treated by dialysis remain a useful marker of prostatic disease.
UR - http://www.scopus.com/inward/record.url?scp=0029098756&partnerID=8YFLogxK
U2 - 10.1111/j.1464-410X.1995.tb07751.x
DO - 10.1111/j.1464-410X.1995.tb07751.x
M3 - Article
C2 - 7551887
VL - 76
SP - 482
EP - 483
JO - British journal of urology
JF - British journal of urology
IS - 4
ER -