Presence and severity of non-alcoholic fatty liver disease in a large prospective primary care cohort

Research output: Contribution to journalArticle

Standard

Presence and severity of non-alcoholic fatty liver disease in a large prospective primary care cohort. / Armstrong, Matthew; Houlihan, Diarmaid; Bentham, Louise; Shaw, Jean; Cramb, Robert; Olliff, S; Gill, Paramjit; Neuberger, James; Lilford, Richard; Newsome, Philip.

In: Journal of Hepatology, Vol. 56, No. 1, 01.01.2012, p. 234-240.

Research output: Contribution to journalArticle

Harvard

APA

Vancouver

Author

Bibtex

@article{2c135c7cc30b4a06b27adc05f3c980e6,
title = "Presence and severity of non-alcoholic fatty liver disease in a large prospective primary care cohort",
abstract = "Background & Aims: Non-alcoholic fatty liver disease (NAFLD) is a common cause of abnormal LFTs in primary care, but there are no data defining its contribution nor reporting the range of NAFLD severity in this setting. This study seeks to calculate the range of disease severity of NAFLD in a primary care setting. Methods: Adult patients with incidental abnormal LFTs, in the absence of a previous history, or current symptoms/ signs of liver disease were prospectively recruited from eight primary care practices in Birmingham. NAFLD was diagnosed as fatty liver on ultrasound, negative serological liver aetiology screen, and alcohol consumption 0.676) suggesting the presence of advanced liver fibrosis was found in 7.6% of NAFLD subjects, whereas 57.2% of NAFLD patients had a low NFS (",
keywords = "Non-alcoholic fatty liver, Fibrosis, Liver function test, Primary care",
author = "Matthew Armstrong and Diarmaid Houlihan and Louise Bentham and Jean Shaw and Robert Cramb and S Olliff and Paramjit Gill and James Neuberger and Richard Lilford and Philip Newsome",
year = "2012",
month = jan,
day = "1",
doi = "10.1016/j.jhep.2011.03.020",
language = "English",
volume = "56",
pages = "234--240",
journal = "Journal of Hepatology",
issn = "0168-8278",
publisher = "Elsevier",
number = "1",

}

RIS

TY - JOUR

T1 - Presence and severity of non-alcoholic fatty liver disease in a large prospective primary care cohort

AU - Armstrong, Matthew

AU - Houlihan, Diarmaid

AU - Bentham, Louise

AU - Shaw, Jean

AU - Cramb, Robert

AU - Olliff, S

AU - Gill, Paramjit

AU - Neuberger, James

AU - Lilford, Richard

AU - Newsome, Philip

PY - 2012/1/1

Y1 - 2012/1/1

N2 - Background & Aims: Non-alcoholic fatty liver disease (NAFLD) is a common cause of abnormal LFTs in primary care, but there are no data defining its contribution nor reporting the range of NAFLD severity in this setting. This study seeks to calculate the range of disease severity of NAFLD in a primary care setting. Methods: Adult patients with incidental abnormal LFTs, in the absence of a previous history, or current symptoms/ signs of liver disease were prospectively recruited from eight primary care practices in Birmingham. NAFLD was diagnosed as fatty liver on ultrasound, negative serological liver aetiology screen, and alcohol consumption 0.676) suggesting the presence of advanced liver fibrosis was found in 7.6% of NAFLD subjects, whereas 57.2% of NAFLD patients had a low NFS (

AB - Background & Aims: Non-alcoholic fatty liver disease (NAFLD) is a common cause of abnormal LFTs in primary care, but there are no data defining its contribution nor reporting the range of NAFLD severity in this setting. This study seeks to calculate the range of disease severity of NAFLD in a primary care setting. Methods: Adult patients with incidental abnormal LFTs, in the absence of a previous history, or current symptoms/ signs of liver disease were prospectively recruited from eight primary care practices in Birmingham. NAFLD was diagnosed as fatty liver on ultrasound, negative serological liver aetiology screen, and alcohol consumption 0.676) suggesting the presence of advanced liver fibrosis was found in 7.6% of NAFLD subjects, whereas 57.2% of NAFLD patients had a low NFS (

KW - Non-alcoholic fatty liver

KW - Fibrosis

KW - Liver function test

KW - Primary care

U2 - 10.1016/j.jhep.2011.03.020

DO - 10.1016/j.jhep.2011.03.020

M3 - Article

C2 - 21703178

VL - 56

SP - 234

EP - 240

JO - Journal of Hepatology

JF - Journal of Hepatology

SN - 0168-8278

IS - 1

ER -