Photocontrolled binding and binding-controlled photochromism within anthracene-modified DNA

Research output: Contribution to journalArticlepeer-review


  • Jack Manchester
  • Dario M Bassani
  • Joseph S Vyle
  • Zheng-yun Zhao

Colleges, School and Institutes


Modified DNA strands undergo a reversible light-induced reaction involving the intramolecular photodimerization of two appended anthracene tags. The photodimers exhibit markedly different binding behavior toward a complementary strand that depends on the number of bases between the modified positions. By preforming the duplex, photochromism can be suppressed, illustrating dual-mode gated behavior.


Original languageEnglish
Pages (from-to)10791-4
Number of pages4
JournalJournal of the American Chemical Society
Issue number26
Publication statusPublished - 2012