Phase 1-2 safety, efficacy and pharmacokinetic study of decitabine in sequential administration with cytarabine in children with relapsed or refractory acute myeloid leukaemia

Pamela Kearns; Christian M Zwaan; Dirk Reinhardt; Brenda Gibson; Lucas Moreno; Karsten Nysom; Susumu Nakahara; Fei Huang; Wangda Zhou; Dolly A Parasrampuria; Sepideh Nemat

doi:10.1111/bjh.15847

Phase 1-2 safety, efficacy and pharmacokinetic study of decitabine in sequential administration with cytarabine in children with relapsed or refractory acute myeloid leukaemia

Pamela Kearns^*, Christian M Zwaan, Dirk Reinhardt, Brenda Gibson, Lucas Moreno, Karsten Nysom, Susumu Nakahara, Fei Huang, Wangda Zhou, Dolly A Parasrampuria, Sepideh Nemat

^*Corresponding author for this work

Cancer Clinical Trials Unit

Research output: Contribution to journal › Letter › peer-review

Original language	English
Pages (from-to)	e7-e11
Number of pages	4
Journal	British Journal of Haematology
Volume	186
Issue number	3
Early online date	7 Mar 2019
DOIs	https://doi.org/10.1111/bjh.15847
Publication status	Published - 1 Aug 2019

Keywords

CDKN2B
DNA methylation
ESR1
acute myeloid leukaemia
cytarabine
decitabine

ASJC Scopus subject areas

Hematology

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10.1111/bjh.15847Licence: None: All rights reserved

Cite this

Kearns, P., Zwaan, C. M., Reinhardt, D., Gibson, B., Moreno, L., Nysom, K., Nakahara, S., Huang, F., Zhou, W., Parasrampuria, D. A., & Nemat, S. (2019). Phase 1-2 safety, efficacy and pharmacokinetic study of decitabine in sequential administration with cytarabine in children with relapsed or refractory acute myeloid leukaemia. British Journal of Haematology, 186(3), e7-e11. https://doi.org/10.1111/bjh.15847

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keywords = "CDKN2B, DNA methylation, ESR1, acute myeloid leukaemia, cytarabine, decitabine",

author = "Pamela Kearns and Zwaan, {Christian M} and Dirk Reinhardt and Brenda Gibson and Lucas Moreno and Karsten Nysom and Susumu Nakahara and Fei Huang and Wangda Zhou and Parasrampuria, {Dolly A} and Sepideh Nemat",

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Kearns, P, Zwaan, CM, Reinhardt, D, Gibson, B, Moreno, L, Nysom, K, Nakahara, S, Huang, F, Zhou, W, Parasrampuria, DA & Nemat, S 2019, 'Phase 1-2 safety, efficacy and pharmacokinetic study of decitabine in sequential administration with cytarabine in children with relapsed or refractory acute myeloid leukaemia', British Journal of Haematology, vol. 186, no. 3, pp. e7-e11. https://doi.org/10.1111/bjh.15847

Phase 1-2 safety, efficacy and pharmacokinetic study of decitabine in sequential administration with cytarabine in children with relapsed or refractory acute myeloid leukaemia. / Kearns, Pamela; Zwaan, Christian M; Reinhardt, Dirk et al.
In: British Journal of Haematology, Vol. 186, No. 3, 01.08.2019, p. e7-e11.

Research output: Contribution to journal › Letter › peer-review

TY - JOUR

T1 - Phase 1-2 safety, efficacy and pharmacokinetic study of decitabine in sequential administration with cytarabine in children with relapsed or refractory acute myeloid leukaemia

AU - Kearns, Pamela

AU - Zwaan, Christian M

AU - Reinhardt, Dirk

AU - Gibson, Brenda

AU - Moreno, Lucas

AU - Nysom, Karsten

AU - Nakahara, Susumu

AU - Huang, Fei

AU - Zhou, Wangda

AU - Parasrampuria, Dolly A

AU - Nemat, Sepideh

PY - 2019/8/1

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KW - DNA methylation

KW - ESR1

KW - acute myeloid leukaemia

KW - cytarabine

KW - decitabine

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U2 - 10.1111/bjh.15847

DO - 10.1111/bjh.15847

M3 - Letter

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JF - British Journal of Haematology

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